INT134981

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Context Info
Confidence 0.49
First Reported 2006
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.69
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (IL1B) signal transduction (IL1B) extracellular space (IL1B)
aging (IL1B) extracellular region (IL1B) cell-cell signaling (IL1B)
IL1B (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 2 100.00 Very High Very High Very High
cytokine 3 50.00 Quite Low
headache 2 5.00 Very Low Very Low Very Low
backache 2 5.00 Very Low Very Low Very Low
Chronic pancreatitis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 2 100.00 Very High Very High Very High
Pancreatitis 3 95.28 Very High Very High Very High
Apoptosis 7 91.56 High High
Adhesions 1 70.60 Quite High
Venezuelan Equine Encephalomyelitis 9 50.00 Quite Low
Togavirus Infection 2 46.48 Quite Low
Infection 10 30.64 Quite Low
Viral Infection 2 21.44 Low Low
Vomiting 4 5.00 Very Low Very Low Very Low
Disease 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Exposure to the VEEV has also induced the up regulation of pro-inflammatory genes such as IL-6, IFN-b, IL-1a, IL1-b and the Fas ligand.
Positive_regulation (induced) of Regulation (regulation) of IL1-b associated with inflammation
1) Confidence 0.49 Published 2007 Journal Virol J Section Body Doc Link PMC2042503 Disease Relevance 0.59 Pain Relevance 0.10
RESULTS: At early stages and height of CAP exacerbation, concentrations of IL-1beta, IL-6, IL-8, TNF-gamma and TNFalpha were elevated (951.1 +/- 104.2 pg/ml; 172.8 +/- 24.3 pg/ml; 432.6 +/- 68.5 pg/ml; 823.3 +/- 97.5 pg/ml; 158.7 +/- 19.6 pg/ml, respectively).
Positive_regulation (elevated) of Regulation (concentrations) of IL-1beta
2) Confidence 0.45 Published 2006 Journal Ter. Arkh. Section Body Doc Link 16613100 Disease Relevance 0.10 Pain Relevance 0

General Comments

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