INT135032

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Context Info
Confidence 0.49
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 1.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (SRF) nucleolus (SRF) nucleus (SRF)
transcription factor binding (SRF) cytoplasm (SRF)
SRF (Homo sapiens)
Pain Link Frequency Relevance Heat
repetitive firing 3 100.00 Very High Very High Very High
lacosamide 12 99.78 Very High Very High Very High
sodium channel 1 97.60 Very High Very High Very High
Action potential 1 87.64 High High
gABA 5 80.72 Quite High
Dopamine 1 76.40 Quite High
anticonvulsant 4 75.00 Quite High
Neurotransmitter 1 74.40 Quite High
adenocard 1 64.84 Quite High
antiepileptic Drug 1 53.92 Quite High
Disease Link Frequency Relevance Heat
Neuropathic Pain 1 45.44 Quite Low
Epilepsy 1 44.60 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The voltage-gated sodium channel (VGSC) blocker phenytoin potently blocked sustained repetitive firing (SRF) but, in contrast, 100 microM LCM failed to block SRF.
Negative_regulation (block) of SRF associated with repetitive firing, sodium channel and lacosamide
1) Confidence 0.49 Published 2006 Journal Neuropharmacology Section Abstract Doc Link 16620882 Disease Relevance 0 Pain Relevance 1.03

General Comments

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