INT135044

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Context Info
Confidence 0.31
First Reported 2005
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.85
Pain Relevance 0.58

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nuclear envelope (Ache) extracellular space (Ache) extracellular region (Ache)
cell adhesion (Ache) Golgi apparatus (Ache) plasma membrane (Ache)
Ache (Mus musculus)
Pain Link Frequency Relevance Heat
Neuropeptide 6 100.00 Very High Very High Very High
Opioid 2 88.16 High High
cytokine 8 82.64 Quite High
Enkephalin 2 80.00 Quite High
Dynorphin 2 78.80 Quite High
Cholecystokinin 2 68.32 Quite High
Central nervous system 1 65.88 Quite High
palliative 3 50.00 Quite Low
tolerance 1 23.60 Low Low
Inflammation 10 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Mucositis 74 99.50 Very High Very High Very High
Stress 4 98.38 Very High Very High Very High
Sprains And Strains 1 97.72 Very High Very High Very High
Neurodegenerative Disease 1 92.76 High High
Creutzfeldt Jakob Disease 1 91.48 High High
Adhesions 1 56.24 Quite High
General Immunology 7 50.00 Quite Low
Pathologic Processes 3 47.92 Quite Low
Death 3 43.92 Quite Low
Targeted Disruption 1 36.16 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Using in situ hybridization and immunohistochemistry, we have studied changes in the expression of neuropeptides, acetylcholinesterase and tyrosine hydroxylase in CD1 and FVB wild-type mouse strains, as well as in PrP(C) null mice and in mice overexpressing PrP(C) following intracerebral inoculation with RML or Me7 prions.
Regulation (changes) of Gene_expression (expression) of acetylcholinesterase associated with neuropeptide and sprains and strains
1) Confidence 0.31 Published 2007 Journal Neurobiol. Aging Section Abstract Doc Link 16621165 Disease Relevance 0.28 Pain Relevance 0.42
In closing, and recalling the recent findings of the vagal efferents on immune suppression (30), psychosocial stress, which is an important etiological factor for mucositis, could soon be shown to alter the expression of the acetylcholinesterase gene.
Regulation (alter) of Gene_expression (expression) of acetylcholinesterase gene associated with stress and mucositis
2) Confidence 0.03 Published 2005 Journal Evidence-based Complementary and Alternative Medicine Section Body Doc Link PMC1297502 Disease Relevance 0.56 Pain Relevance 0.16

General Comments

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