INT135079

Context Info Confidence 0.49 First Reported 2006 Last Reported 2006 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0.29

Anatomy Link Frequency neurons 2 Trpm8 (Rattus norvegicus)

Pain Link Frequency Relevance Heat agonist 1 99.96 MU agonist 1 86.16 Central nervous system 1 83.52 Glutamate 3 76.56

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Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Icilin, the peripheral cold channel agonist, activates TRPM8 and TRPA1, localized on dorsal root ganglia and trigeminal neurons in rats.

Positive_regulation (activates) of Localization (localized) of TRPM8 in neurons associated with agonist

1) Confidence 0.49 Published 2006 Journal Amino Acids Section Abstract Doc Link 16622598 Disease Relevance 0 Pain Relevance 0.29

General Comments

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