INT135093

Context Info Confidence 0.37 First Reported 2005 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 6 Total Number 6 Disease Relevance 1.90 Pain Relevance 0.27

Anatomy Link Frequency sympathetic 2 ganglion 1 T2 (Mus musculus)

Pain Link Frequency Relevance Heat anesthesia 3 99.24 Inflammation 17 50.00 corticosteroid 14 5.00 agonist 5 5.00 Pain 2 5.00 imagery 2 5.00 cINOD 1 5.00

Disease Link Frequency Relevance Heat Ganglion Cysts 3 98.60 Skin Appendage Disease 15 93.68 Postoperative Complications 3 82.32 Asthma 55 75.60 Recurrence 4 69.60 Hypersensitivity 2 67.08 INFLAMMATION 19 50.00 Cognitive Disorder 6 5.00 Pain 2 5.00 Respiratory Sounds 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

An additional T3 block should be given if patients received either previous T2 sympathectomy or elevated palmar temperature <1 degrees C after T2 sympathetic block.

Negative_regulation (block) of T2 in sympathetic

1) Confidence 0.37 Published 2005 Journal Int Surg Section Abstract Doc Link 16625948 Disease Relevance 0.52 Pain Relevance 0.09

The level of sympathetic blocks were the T2 and T3 in five patients, only T2 block in four, patients, and only T3 block in seven patients.

Negative_regulation (block) of T2 in sympathetic

2) Confidence 0.37 Published 2005 Journal Int Surg Section Abstract Doc Link 16625948 Disease Relevance 0.54 Pain Relevance 0.08

We performed the T2 sympathetic block for patients with still intact T2 ganglion using an 8-mm, 0 degrees thoracoscope.

Negative_regulation (block) of T2 in ganglion associated with ganglion cysts

3) Confidence 0.37 Published 2005 Journal Int Surg Section Abstract Doc Link 16625948 Disease Relevance 0.41 Pain Relevance 0.10

100 msec for monkey T; even faster for monkey A); the effect of T2 value (blue curve) arises more slowly, but is clearly present in both animals by the time of onset of the motion stimulus.

Negative_regulation (effect) of T2

4) Confidence 0.04 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2824817 Disease Relevance 0 Pain Relevance 0

Even though LIP activity in monkey T does not respond as rapidly or robustly as in monkey A, all major features of the absolute value signal observed in monkey A are replicated in monkey T: 1) the effect of absolute value begins during the reward cue period, 2) greater absolute value is represented by higher firing rates, 3) the effect is maintained until the end of the trial and 4) the effect is present for T2 choice trials as well.

Negative_regulation (present) of T2

5) Confidence 0.04 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2824817 Disease Relevance 0 Pain Relevance 0

Similarly, AEF evaluation showed a significant reduction in the number of episodes in the FeNO group at T2 and T3 (Mean values: from 1.96 ± 1.18 to 1.01 ± 0.96 at T2, p[T1-T2] = 0.0003, and to 0.83 ± 0.98 at T3, p[T1-T3] = 0.0001) but not in the GINA group (Mean values: from 2.01 ± 1.17 to 1.78 ± 1.29 at T2, p[T1-T2] = 0.08; and to 1.85 ± 1.34 at T3, p[T1-T3] = 0.14) (Figure 2).

Negative_regulation (reduction) of T2

6) Confidence 0.02 Published 2010 Journal Journal of Allergy Section Body Doc Link PMC2948939 Disease Relevance 0.43 Pain Relevance 0

General Comments

This test has worked.