INT135112

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Context Info
Confidence 0.44
First Reported 2006
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.30
Pain Relevance 1.58

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Grin1) plasma membrane (Grin1) enzyme binding (Grin1)
cytoplasm (Grin1)
Grin1 (Mus musculus)
Pain Link Frequency Relevance Heat
nMDA receptor 59 100.00 Very High Very High Very High
Morphine 9 100.00 Very High Very High Very High
Hippocampus 12 94.80 High High
antagonist 8 84.80 Quite High
Kinase C 1 68.16 Quite High
tolerance 1 65.44 Quite High
depression 31 50.00 Quite Low
Glutamate receptor 2 8.72 Low Low
long-term potentiation 20 5.00 Very Low Very Low Very Low
tail-flick 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 1 89.16 High High
Repression 1 80.52 Quite High
Reperfusion Injury 1 63.12 Quite High
Targeted Disruption 21 62.24 Quite High
Depression 31 50.00 Quite Low
Anxiety Disorder 24 50.00 Quite Low
Shock 9 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
Nociception 3 5.00 Very Low Very Low Very Low
Brain Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
At designated periods, slices were preserved for immunoblot analysis to observe effects of morphine pretreatment on membrane translocation and total protein expression of nPKCepsilon and phosphorylation of NR1 subunits of NMDA receptors.
Regulation (effects) of Phosphorylation (phosphorylation) of NR1 associated with nmda receptor and morphine
1) Confidence 0.44 Published 2006 Journal J Neurosurg Anesthesiol Section Abstract Doc Link 16628065 Disease Relevance 0.15 Pain Relevance 1.00
We found no change in the phosphorylation of NMDA receptor subunits NR1, NR2A or NR2B in TgDREAM mice (Figure 5B).
Neg (no) Regulation (change) of Phosphorylation (phosphorylation) of NR1 associated with nmda receptor
2) Confidence 0.21 Published 2010 Journal Mol Brain Section Body Doc Link PMC2822766 Disease Relevance 0.14 Pain Relevance 0.58

General Comments

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