INT135122

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.11
First Reported 2007
Last Reported 2007
Negated 1
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 2.08
Pain Relevance 0.97

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (GJA8) plasma membrane (GJA8)
GJA8 (Homo sapiens)
Pain Link Frequency Relevance Heat
Etanercept 12 95.08 Very High Very High Very High
Adalimumab 66 94.44 High High
Infliximab 130 93.96 High High
ischemia 1 93.60 High High
Inflammation 29 86.08 High High
Angina 7 72.84 Quite High
Potency 2 55.60 Quite High
Bioavailability 4 41.76 Quite Low
cytokine 8 32.48 Quite Low
corticosteroid 32 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pathologic Dilatation 16 100.00 Very High Very High Very High
Hypertension 6 97.84 Very High Very High Very High
Nicotine Addiction 2 97.28 Very High Very High Very High
Hyperlipidemia 1 96.76 Very High Very High Very High
Diabetes Mellitus 3 87.44 High High
Obesity 1 84.40 Quite High
Heart Rate Under Development 1 73.16 Quite High
Angina 4 72.84 Quite High
Cv General 3 Under Development 3 70.92 Quite High
Coronary Stenosis 2 61.76 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CAE appears to be associated with traditional cardiovascular risk factors such as hypertension, smoking, and hyperlipidemia.
CAE Binding (associated) of associated with nicotine addiction, hypertension, hyperlipidemia and pathologic dilatation
1) Confidence 0.11 Published 2007 Journal Angiology Section Abstract Doc Link 18216379 Disease Relevance 1.56 Pain Relevance 0.33
In conclusion, CAE was found to be associated with prolonged QT interval and increased QTd.
CAE Binding (associated) of associated with pathologic dilatation
2) Confidence 0.10 Published 2007 Journal J Electrocardiol Section Abstract Doc Link 16631193 Disease Relevance 0.53 Pain Relevance 0.12
Since it lacks the Fc portion of the antibody, CZP only exerts its activity through binding to soluble and membrane-bound TNF-alfa, and cannot bind to cell-surface receptors for antibodies; consequently, complement fixation and cell lysis do not occur.
CZP Binding (binding) of
3) Confidence 0.06 Published 2007 Journal Core Evidence Section Body Doc Link PMC3012434 Disease Relevance 0 Pain Relevance 0.23
Since it lacks the Fc portion of the antibody, CZP only exerts its activity through binding to soluble and membrane-bound TNF-alfa, and cannot bind to cell-surface receptors for antibodies; consequently, complement fixation and cell lysis do not occur.
CZP Neg (cannot) Binding (bind) of
4) Confidence 0.04 Published 2007 Journal Core Evidence Section Body Doc Link PMC3012434 Disease Relevance 0 Pain Relevance 0.29

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox