INT135207

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Context Info
Confidence 0.07
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.48
Pain Relevance 0.69

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleolus (Gmeb1, Tfap2a) nucleus (Gmeb1, Tfap2a) cytoplasm (Gmeb1, Tfap2a)
cytosol (Tfap2a) Golgi apparatus (Tfap2a) DNA binding (Gmeb1)
Anatomy Link Frequency
poly 2
Gmeb1 (Rattus norvegicus)
Tfap2a (Rattus norvegicus)
Pain Link Frequency Relevance Heat
fluoxetine 7 98.28 Very High Very High Very High
depression 1 85.40 High High
carbamazepine 2 72.00 Quite High
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 2 93.92 High High
Depression 1 85.40 High High
Manic Depressive Disorder 3 81.36 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Transcription factors (activator protein-1, activator protein-2, glucocorticoid response element, polyoma enhancer element-3 and nuclear factor-kappa B) that are known to regulate cPLA(2) gene expression were not significantly changed by chronic fluoxetine, but nuclear AU-rich element/poly(U)-binding/degradation factor-1 RNA-stabilizing protein was increased significantly.
glucocorticoid response element Regulation (regulate) of Gene_expression (expression) of activator protein-2 in poly associated with fluoxetine
1) Confidence 0.07 Published 2006 Journal Pharmacogenomics J. Section Abstract Doc Link 16636684 Disease Relevance 0.48 Pain Relevance 0.69

General Comments

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