INT135234

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Context Info
Confidence 0.29
First Reported 2005
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 13
Total Number 15
Disease Relevance 10.80
Pain Relevance 3.40

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (ETFDH) mitochondrion (ETFDH) small molecule metabolic process (ETFDH)
oxidoreductase activity (ETFDH)
Anatomy Link Frequency
Knee 2
joint 1
juvenile 1
ETFDH (Homo sapiens)
Pain Link Frequency Relevance Heat
Osteoarthritis 192 100.00 Very High Very High Very High
Pain 85 100.00 Very High Very High Very High
Arthritis 9 99.86 Very High Very High Very High
headache 213 99.82 Very High Very High Very High
rheumatoid arthritis 1 94.72 High High
depression 46 75.00 Quite High
Migraine 85 59.68 Quite High
Cluster headache 1 56.60 Quite High
Angina 1 40.88 Quite Low
addiction 4 40.20 Quite Low
Disease Link Frequency Relevance Heat
Knee Osteoarthritis 188 100.00 Very High Very High Very High
Pain 85 100.00 Very High Very High Very High
Reprotox - General 1 84 100.00 Very High Very High Very High
Cancer 83 100.00 Very High Very High Very High
Carcinoid 2 100.00 Very High Very High Very High
Disease 91 99.98 Very High Very High Very High
Arthritis 9 99.86 Very High Very High Very High
Cirrhosis 104 99.84 Very High Very High Very High
Headache 233 99.82 Very High Very High Very High
Acromegaly 32 99.58 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Nevertheless, some domains of QoL in prostate cancer patients are negatively affected compared to the general population.
Regulation (affected) of QoL associated with reprotox - general 1
1) Confidence 0.29 Published 2010 Journal GMS Psycho-Social-Medicine Section Body Doc Link PMC2899861 Disease Relevance 0.79 Pain Relevance 0.24
It has been reported that several domains of QoL in cancer patients with carcinoid tumors were negatively affected in comparison to the general population [19], [24].
Regulation (affected) of QoL associated with carcinoid and cancer
2) Confidence 0.29 Published 2010 Journal GMS Psycho-Social-Medicine Section Body Doc Link PMC2899861 Disease Relevance 0.95 Pain Relevance 0.05
There was also some ambiguity related to the component that actually affected the QoL in the present study.
Regulation (affected) of QoL
3) Confidence 0.25 Published 2005 Journal Health Qual Life Outcomes Section Body Doc Link PMC1156929 Disease Relevance 0.26 Pain Relevance 0
Arthritis in BD affects considerably patients' pain levels and QoL.
Regulation (affects) of QoL associated with pain, disease and arthritis
4) Confidence 0.21 Published 2006 Journal Clin. Rheumatol. Section Abstract Doc Link 16639519 Disease Relevance 2.40 Pain Relevance 0.75
Difference between then-test and post-test score, reflecting the change in QoL having allowed for response shift.
Regulation (change) of QoL
5) Confidence 0.14 Published 2005 Journal Health Qual Life Outcomes Section Body Doc Link PMC1079917 Disease Relevance 0 Pain Relevance 0
According to our knowledge this was the first study that evaluated the effects of an educational/ self-care program on the QoL of cirrhotic patients.
Regulation (effects) of QoL associated with cirrhosis
6) Confidence 0.11 Published 2005 Journal Health Qual Life Outcomes Section Body Doc Link PMC1156929 Disease Relevance 0.86 Pain Relevance 0
However, we do not know exactly to which component the changes in QoL might be attributed.
Regulation (changes) of QoL
7) Confidence 0.11 Published 2005 Journal Health Qual Life Outcomes Section Body Doc Link PMC1156929 Disease Relevance 0.24 Pain Relevance 0.06
So, further study is suggested to know to which component the change in QoL might be attributed.


Regulation (change) of QoL
8) Confidence 0.11 Published 2005 Journal Health Qual Life Outcomes Section Body Doc Link PMC1156929 Disease Relevance 0.24 Pain Relevance 0
Knee OA negatively affects the QoL and physical function in both genders, but women are more adversely affected than men.



Regulation (affects) of QoL in Knee associated with osteoarthritis
9) Confidence 0.07 Published 2010 Journal BMC Musculoskelet Disord Section Abstract Doc Link PMC2898694 Disease Relevance 1.03 Pain Relevance 0.55
The aim of this study was to examine the influence of radiographic knee OA, specifically tibiofemoral OA, on the QoL and function among elderly community residents in Korea.
Spec (examine) Regulation (influence) of QoL in knee associated with osteoarthritis
10) Confidence 0.07 Published 2010 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2898694 Disease Relevance 1.09 Pain Relevance 0.47
This has important implications for assessing the effects of treatments as a change in QoL may reflect a response shift, a treatment effect, or a complex combination of both.
Regulation (change) of QoL
11) Confidence 0.03 Published 2005 Journal Health Qual Life Outcomes Section Abstract Doc Link PMC1236951 Disease Relevance 0.08 Pain Relevance 0
Powers and colleagues (2003) found that in their study of 572 pediatric patients between the ages of 5- and 18-years referred to a headache clinic, QoL was adversely affected in all areas of functioning when compared to healthy controls, and the impact on QoL was similar to that of children with juvenile rheumatoid arthritis and cancer.
Regulation (affected) of QoL in juvenile associated with cancer, rheumatoid arthritis and headache
12) Confidence 0.01 Published 2008 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2526375 Disease Relevance 1.50 Pain Relevance 1.27
Therefore, it is likely that other factors in our patients with GHD after treatment for acromegaly explain the lack of effect on QoL during rhGH replacement, such as persisting joint related complaints [35] and/or unfavorable late effects of previous radiotherapy [36].
Regulation (effect) of QoL in joint associated with acromegaly and growth hormone deficiency
13) Confidence 0.00 Published 2009 Journal Pituitary Section Body Doc Link PMC2764055 Disease Relevance 1.25 Pain Relevance 0
Secondary objectives of the study were to verify the effect of the simplification strategy on QoL, to verify patientsÂ’ preferences, to verify how adherence and QoL could change over time, and to establish virologic and immunologic outcomes of the simplified regimen.
Regulation (effect) of QoL
14) Confidence 0.00 Published 2010 Journal Patient Prefer Adherence Section Body Doc Link PMC2875721 Disease Relevance 0.05 Pain Relevance 0
In this trial we evaluated how therapy simplification could affect adherence, QoL and subjective perception of health status and how these variables did influence one another.


Regulation (affect) of QoL
15) Confidence 0.00 Published 2010 Journal Patient Prefer Adherence Section Body Doc Link PMC2875721 Disease Relevance 0.06 Pain Relevance 0

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