INT135360

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Context Info
Confidence 0.03
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.19
Pain Relevance 0.51

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (Aadac) enzyme binding (Mecp2) embryo development (Mecp2)
DNA binding (Mecp2) protein complex (Mecp2) lipid metabolic process (Aadac)
Mecp2 (Rattus norvegicus)
Aadac (Rattus norvegicus)
Pain Link Frequency Relevance Heat
fluoxetine 8 75.60 Quite High
cocaine 4 75.00 Quite High
Nortriptyline 2 60.24 Quite High
Serotonin 6 25.00 Low Low
Hippocampus 2 25.00 Low Low
GABAergic 2 25.00 Low Low
Disease Link Frequency Relevance Heat
Retts Disease 2 94.72 High High
Urological Neuroanatomy 2 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Once bound to methylated CpG sites, methyl-CpG-binding protein 2 (MeCP2) is thought to silence transcription of downstream genes by recruiting a histone deacetylase (HDAC).
methyl-CpG-binding protein 2 Binding (recruiting) of deacetylase
1) Confidence 0.03 Published 2006 Journal Mol. Pharmacol. Section Abstract Doc Link 16670375 Disease Relevance 0.09 Pain Relevance 0.26
Once bound to methylated CpG sites, methyl-CpG-binding protein 2 (MeCP2) is thought to silence transcription of downstream genes by recruiting a histone deacetylase (HDAC).
MeCP2 Binding (recruiting) of deacetylase
2) Confidence 0.03 Published 2006 Journal Mol. Pharmacol. Section Abstract Doc Link 16670375 Disease Relevance 0.09 Pain Relevance 0.26

General Comments

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