INT135447

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Context Info
Confidence 0.63
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 5
Total Number 6
Disease Relevance 1.55
Pain Relevance 1.64

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

ATPase activity (Abcc8) plasma membrane (Abcc8) transmembrane transport (Abcc8)
Anatomy Link Frequency
neurons 2
pancreas 1
brain 1
dorsal root ganglia 1
heart 1
Abcc8 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Pain 19 95.56 Very High Very High Very High
Peripheral nerve injury 2 90.76 High High
antiallodynic 6 89.44 High High
Neurotransmitter 6 85.76 High High
Arthritis 2 75.00 Quite High
allodynia 1 67.96 Quite High
Migraine 3 66.64 Quite High
headache 9 65.96 Quite High
Analgesic 3 53.52 Quite High
unmyelinated 2 52.40 Quite High
Disease Link Frequency Relevance Heat
Pressure And Volume Under Development 1 97.96 Very High Very High Very High
Arthritis 6 93.24 High High
Nervous System Injury 18 90.76 High High
Pain 2 89.56 High High
Nociception 3 81.08 Quite High
Neuropathic Pain 19 67.96 Quite High
Headache 12 66.64 Quite High
Hypercalcemia 1 49.24 Quite Low
Hyperalgesia 14 25.00 Low Low
Injury 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Distribution of SUR1 expression in NF200+ and NF200- neurons from control rats, and alterations after axotomy (Fig. 6)
Transcription (Distribution) of SUR1 in neurons
1) Confidence 0.63 Published 2010 Journal Mol Pain Section Body Doc Link PMC2825500 Disease Relevance 0 Pain Relevance 0.03
Among K+ ATP channel subunits, mRNAs for Kir6.1, SUR1, SUR2A and SUR2B were abundant in rat dorsal root ganglia, while Kir6.2 mRNA was poor.
Transcription (abundant) of SUR1 in dorsal root ganglia
2) Confidence 0.49 Published 2006 Journal Neuropharmacology Section Abstract Doc Link 16678221 Disease Relevance 0.64 Pain Relevance 0.53
PCR demonstrated Kir6.1, Kir6.2, SUR1 and SUR2 transcripts in control DRG neurons.
Transcription (transcripts) of SUR1 in neurons
3) Confidence 0.49 Published 2010 Journal Mol Pain Section Abstract Doc Link PMC2825500 Disease Relevance 0.18 Pain Relevance 0.35
The mRNA transcripts of SUR1 and Kir6.2 subunits were predominantly found in brain, pancreas and heart, while SUR2A mRNA was merely detected within the heart.
Transcription (transcripts) of SUR1 in pancreas
4) Confidence 0.25 Published 2010 Journal Eur. J. Pharmacol. Section Abstract Doc Link 20361954 Disease Relevance 0.24 Pain Relevance 0.24
The mRNA transcripts of SUR1 and Kir6.2 subunits were predominantly found in brain, pancreas and heart, while SUR2A mRNA was merely detected within the heart.
Transcription (transcripts) of SUR1 in brain
5) Confidence 0.08 Published 2010 Journal Eur. J. Pharmacol. Section Abstract Doc Link 20361954 Disease Relevance 0.24 Pain Relevance 0.24
The mRNA transcripts of SUR1 and Kir6.2 subunits were predominantly found in brain, pancreas and heart, while SUR2A mRNA was merely detected within the heart.
Transcription (transcripts) of SUR1 in heart
6) Confidence 0.08 Published 2010 Journal Eur. J. Pharmacol. Section Abstract Doc Link 20361954 Disease Relevance 0.24 Pain Relevance 0.24

General Comments

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