INT135487

Context Info Confidence 0.05 First Reported 2006 Last Reported 2006 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.05 Pain Relevance 0.18

signal transduction (Prkar1b) cytoplasm (Prkar1b)

Anatomy Link Frequency myotube 1 Prkar1b (Rattus norvegicus)

Pain Link Frequency Relevance Heat sodium channel 2 98.72 tetrodotoxin 1 87.52

Disease Link Frequency Relevance Heat Apoptosis 1 50.72

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

In contrast, the promotion of electrical activity in myotube cultures, induced by the up-regulation of voltage-dependent sodium channels or by direct stimulation with extracellular electrodes, causes TbetaRI levels to decrease.

Negative_regulation (decrease) of TbetaRI in myotube associated with sodium channel

1) Confidence 0.05 Published 2006 Journal J. Biol. Chem. Section Abstract Doc Link 16682418 Disease Relevance 0.05 Pain Relevance 0.18

General Comments

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