INT135516

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Context Info
Confidence 0.12
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 1.62

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (PRKCA, OPRM1) plasma membrane (PRKCA, OPRM1) nucleoplasm (PRKCA)
mitochondrion (PRKCA) small molecule metabolic process (PRKCA) Golgi apparatus (OPRM1)
PRKCA (Homo sapiens)
OPRM1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Kinase C 6 100.00 Very High Very High Very High
Morphine 13 98.12 Very High Very High Very High
agonist 2 77.32 Quite High
opioid receptor 4 75.00 Quite High
potassium channel 3 72.32 Quite High
Enkephalin 1 59.76 Quite High
MU agonist 2 57.96 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The PKC inhibitor bisindolylmaleimide 1 (GF109203X) inhibited MOR1 phosphorylation under basal conditions and in the presence of morphine, but it did not inhibit DAMGO-induced phosphorylation.
PKC Negative_regulation (inhibited) of Phosphorylation (phosphorylation) of MOR1 associated with kinase c and morphine
1) Confidence 0.12 Published 2006 Journal Mol. Pharmacol. Section Abstract Doc Link 16682505 Disease Relevance 0 Pain Relevance 1.62

General Comments

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