INT135585

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Context Info
Confidence 0.13
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 2.51
Pain Relevance 0.95

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (CSF2, CCL2) extracellular region (CSF2, CCL2) signal transduction (CCL2)
aging (CCL2) cell adhesion (CCL2) cytoskeleton organization (CCL2)
Anatomy Link Frequency
T cell 2
CSF2 (Homo sapiens)
CCL2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 16 97.20 Very High Very High Very High
addiction 2 96.80 Very High Very High Very High
cINOD 2 89.76 High High
cytokine 2 76.64 Quite High
corticosteroid 6 66.44 Quite High
dexamethasone 4 48.24 Quite Low
Disease Link Frequency Relevance Heat
Adhesions 2 98.00 Very High Very High Very High
INFLAMMATION 18 97.20 Very High Very High Very High
Necrosis 2 78.76 Quite High
Disease 4 78.56 Quite High
Cancer 2 78.40 Quite High
Asthma 6 63.76 Quite High
Pulmonary Disease 8 62.44 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Therefore, we have used adenoviral overexpression to demonstrate NF-kappaB and IKK2 dependence of key inflammatory genes, including intercellular adhesion molecule (ICAM)-1, cyclooxygenase-2, IL-6, IL-8, granulocyte macrophage-colony-stimulating factor (GM-CSF), regulated on activation normal T cell expressed and secreted (RANTES), monocyte chemotactic protein-1 (MCP-1), growth-regulated oncogene-alpha (GROalpha), neutrophil-activating protein-2 (NAP-2), and epithelial neutrophil activating peptide 78 (ENA-78) in primary human airways smooth muscle cells.
GM-CSF Regulation (regulated) of monocyte chemotactic protein-1 in T cell associated with addiction, inflammation and adhesions
1) Confidence 0.13 Published 2006 Journal Mol. Pharmacol. Section Abstract Doc Link 16687566 Disease Relevance 1.25 Pain Relevance 0.47
Therefore, we have used adenoviral overexpression to demonstrate NF-kappaB and IKK2 dependence of key inflammatory genes, including intercellular adhesion molecule (ICAM)-1, cyclooxygenase-2, IL-6, IL-8, granulocyte macrophage-colony-stimulating factor (GM-CSF), regulated on activation normal T cell expressed and secreted (RANTES), monocyte chemotactic protein-1 (MCP-1), growth-regulated oncogene-alpha (GROalpha), neutrophil-activating protein-2 (NAP-2), and epithelial neutrophil activating peptide 78 (ENA-78) in primary human airways smooth muscle cells.
GM-CSF Regulation (regulated) of MCP-1 in T cell associated with addiction, inflammation and adhesions
2) Confidence 0.12 Published 2006 Journal Mol. Pharmacol. Section Abstract Doc Link 16687566 Disease Relevance 1.25 Pain Relevance 0.47

General Comments

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