INT135587

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Context Info
Confidence 0.18
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.28
Pain Relevance 0.48

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (IKBKE, NFKB1) cytosol (IKBKE, NFKB1) nucleus (IKBKE, NFKB1)
nucleoplasm (NFKB1) mitochondrion (NFKB1) signal transduction (NFKB1)
IKBKE (Homo sapiens)
NFKB1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 1 98.26 Very High Very High Very High
Inflammation 8 95.20 Very High Very High Very High
cINOD 1 91.28 High High
corticosteroid 3 86.32 High High
addiction 1 82.56 Quite High
dexamethasone 2 25.00 Low Low
Disease Link Frequency Relevance Heat
Necrosis 1 99.32 Very High Very High Very High
Cancer 1 99.14 Very High Very High Very High
INFLAMMATION 9 95.20 Very High Very High Very High
Asthma 3 83.64 Quite High
Pulmonary Disease 4 82.32 Quite High
Adhesions 1 77.60 Quite High
Disease 2 38.16 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Proinflammatory cytokines, including interleukin (IL)-1beta and tumor necrosis factor (TNF)-alpha, activate the IkappaB kinase complex (IKK) to promote the degradation of inhibitory IkappaB proteins and activate NF-kappaB.
IkappaB kinase Positive_regulation (activate) of NF-kappaB associated with necrosis, cancer and cytokine
1) Confidence 0.18 Published 2006 Journal Mol. Pharmacol. Section Abstract Doc Link 16687566 Disease Relevance 1.28 Pain Relevance 0.48

General Comments

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