INT135630

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Context Info
Confidence 0.51
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 1.67
Pain Relevance 1.82

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleolus (GON4L) nucleus (GON4L) DNA binding (GON4L)
cytoplasm (GON4L)
Anatomy Link Frequency
GON 2
GON4L (Homo sapiens)
Pain Link Frequency Relevance Heat
Cluster headache 12 99.28 Very High Very High Very High
Sumatriptan 4 94.68 High High
lidocaine 2 94.64 High High
Triptan 2 89.36 High High
Pain 2 88.00 High High
Disease Link Frequency Relevance Heat
Emergencies 4 99.84 Very High Very High Very High
Cluster Headache 12 99.28 Very High Very High Very High
Congenital Anomalies 2 91.24 High High
Pain 2 88.00 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We suppose that the action of GON blockade may involve the trigemino-cervical complex and we moreover strongly suggest to use GON blockade in emergency departments for cluster headache with cervico-occipital spreading as attack abortive therapy, especially in oxygen and sumatriptan resistant cluster headache attacks, in patients who complaints sumatriptan side-effects or have contraindications to use triptans.
Negative_regulation (blockade) of GON in GON associated with sumatriptan, cluster headache, emergencies and triptan
1) Confidence 0.51 Published 2006 Journal J Headache Pain Section Abstract Doc Link 16688413 Disease Relevance 0.84 Pain Relevance 0.95
GON blockade was effective immediately for the attack and the cluster period resolved after the injection.
Negative_regulation (blockade) of GON in GON
2) Confidence 0.38 Published 2006 Journal J Headache Pain Section Abstract Doc Link 16688413 Disease Relevance 0.83 Pain Relevance 0.87

General Comments

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