INT135641

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Context Info
Confidence 0.35
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.34
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Ina) nuclear envelope (Dst) endoplasmic reticulum (Dst)
cytoplasm (Dst) structural molecule activity (Ina) cell motility (Dst)
Anatomy Link Frequency
neuronal 1
Dst (Mus musculus)
Ina (Mus musculus)
Pain Link Frequency Relevance Heat
Hsan 1 59.56 Quite High
Disease Link Frequency Relevance Heat
Neurodegenerative Disease 1 92.60 High High
Dystonia 2 75.00 Quite High
Bullous Skin Disease 1 60.84 Quite High
Hereditary Sensory And Autonomic Neuropathies 1 59.56 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
From our observations, we suggest that the interaction between BPAG1 and alpha-internexin may be one of the key factors involved in neuronal degeneration, and abnormal accumulation of alpha-internexin may impair the axonal transport and subsequently turns on the cascade of neuronal apoptosis in dt mice.
BPAG1 Binding (interaction) of alpha-internexin in neuronal associated with neurodegenerative disease
1) Confidence 0.35 Published 2006 Journal J. Neuropathol. Exp. Neurol. Section Abstract Doc Link 16691115 Disease Relevance 0.34 Pain Relevance 0.06

General Comments

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