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Context Info
Confidence 0.35
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.34
Pain Relevance 0.06

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cell differentiation (Ina) nuclear envelope (Dst) endoplasmic reticulum (Dst)
cytoplasm (Dst) structural molecule activity (Ina) cell motility (Dst)
Anatomy Link Frequency
neuronal 1
Dst (Mus musculus)
Ina (Mus musculus)
Pain Link Frequency Relevance Heat
Hsan 1 59.56 Quite High
Disease Link Frequency Relevance Heat
Neurodegenerative Disease 1 92.60 High High
Dystonia 2 75.00 Quite High
Bullous Skin Disease 1 60.84 Quite High
Hereditary Sensory And Autonomic Neuropathies 1 59.56 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
From our observations, we suggest that the interaction between BPAG1 and alpha-internexin may be one of the key factors involved in neuronal degeneration, and abnormal accumulation of alpha-internexin may impair the axonal transport and subsequently turns on the cascade of neuronal apoptosis in dt mice.
BPAG1 Binding (interaction) of alpha-internexin in neuronal associated with neurodegenerative disease
1) Confidence 0.35 Published 2006 Journal J. Neuropathol. Exp. Neurol. Section Abstract Doc Link 16691115 Disease Relevance 0.34 Pain Relevance 0.06

General Comments

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