INT13573

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Context Info
Confidence 0.00
First Reported 1991
Last Reported 2002
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.86
Pain Relevance 1.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Helt) nucleus (Helt) DNA binding (Helt)
Anatomy Link Frequency
interneurons 2
Helt (Mus musculus)
Pain Link Frequency Relevance Heat
gABA 8 100.00 Very High Very High Very High
GABAergic 5 100.00 Very High Very High Very High
opiate 4 99.70 Very High Very High Very High
Dopamine 1 98.40 Very High Very High Very High
Serotonin 2 92.08 High High
antagonist 6 90.84 High High
agonist 3 86.20 High High
Clonidine 2 80.68 Quite High
Neurotransmitter 1 75.00 Quite High
Dorsal horn 1 55.04 Quite High
Disease Link Frequency Relevance Heat
Shock 3 93.72 High High
Nociception 9 78.24 Quite High
Anxiety Disorder 5 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, the available evidence indicates that exogenous opiates activate off-cells by inhibiting GABAergic release.
Negative_regulation (inhibiting) of Localization (release) of GABAergic associated with gabaergic and opiate
1) Confidence 0.00 Published 1991 Journal Annu. Rev. Neurosci. Section Abstract Doc Link 1674413 Disease Relevance 0.39 Pain Relevance 0.40
This may be due to yohimbine's lack of specificity and its ability to inhibit GABAergic release.
Negative_regulation (inhibit) of Localization (release) of GABAergic associated with gabaergic
2) Confidence 0.00 Published 1994 Journal Life Sci. Section Abstract Doc Link 7906377 Disease Relevance 0.46 Pain Relevance 0.52
Heroin has been hypothesized to activate opiate receptors and inhibit gamma-aminobutyric acid (GABA) release from inhibitory GABAergic interneurons which, in turn, activates dopamine projection cells.
Negative_regulation (inhibit) of Localization (release) of GABAergic in interneurons associated with dopamine, gaba, gabaergic and opiate
3) Confidence 0.00 Published 2002 Journal Magn Reson Med Section Abstract Doc Link 12417998 Disease Relevance 0 Pain Relevance 0.34

General Comments

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