INT135731

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Context Info
Confidence 0.29
First Reported 2005
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 5
Disease Relevance 5.05
Pain Relevance 0.30

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (NAE1) plasma membrane (NAE1) cell cycle (NAE1)
cytoplasm (NAE1)
Anatomy Link Frequency
viscera 2
mesentery 1
NAE1 (Homo sapiens)
Pain Link Frequency Relevance Heat
abdominal pain 20 89.68 High High
Angina 1 53.08 Quite High
Pain 1 49.72 Quite Low
Inflammation 1 49.28 Quite Low
headache 1 44.92 Quite Low
Disease Link Frequency Relevance Heat
Cancer 95 99.14 Very High Very High Very High
Gastrointestinal Stromal Tumor 92 98.12 Very High Very High Very High
Uterine Fibroids 8 95.20 Very High Very High Very High
Leiomyosarcoma 2 94.24 High High
Epithelioid Leiomyoma 2 93.76 High High
Recurrence 10 92.96 High High
Hemorrhage 54 90.48 High High
Abdominal Pain 20 89.68 High High
Shock 1 88.32 High High
Metastasis 8 87.60 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, no statistically significant expression of this protooncogene-related protein was observed at the doses of 0, 100, or 300 microg/mL or within the dose range of 0-200 microg/mL for 2,6-DNT.
Gene_expression (expression) of protooncogene-related protein
1) Confidence 0.29 Published 2005 Journal Int J Environ Res Public Health Section Abstract Doc Link 16705839 Disease Relevance 0.62 Pain Relevance 0.05
Gastrointestinal stromal tumor (GIST) is a generic name for a mesenchymal tumor originating in the muscular wall of a hollow viscera that expresses the c-kit proto-oncogen protein.
Gene_expression (expresses) of proto-oncogen protein in viscera associated with cancer and gastrointestinal stromal tumor
2) Confidence 0.05 Published 2008 Journal World J Surg Oncol Section Body Doc Link PMC2486266 Disease Relevance 1.51 Pain Relevance 0
Gastrointestinal stromal tumor (GIST) is a generic name for a mesenchymal tumor originating in the muscular wall of hollow viscera that expresses the c-kit proto-oncogen protein [1-3].
Gene_expression (expresses) of proto-oncogen protein in viscera associated with cancer and gastrointestinal stromal tumor
3) Confidence 0.05 Published 2008 Journal World J Surg Oncol Section Body Doc Link PMC2486266 Disease Relevance 0.78 Pain Relevance 0
Gastrointestinal stromal tumors (GIST) constitute a large majority of mesenchymal tumors of the gastrointestinal (GI) tract, which express the c-kit proto-oncogene protein, a cell membrane receptor with tyrosine kinase activity.
Gene_expression (express) of proto-oncogene protein associated with cancer and gastrointestinal stromal tumor
4) Confidence 0.02 Published 2005 Journal World J Surg Oncol Section Abstract Doc Link PMC549541 Disease Relevance 0.86 Pain Relevance 0.17
Gastrointestinal stromal tumors (GIST) are the most common form of mesenchymal tumors arising from the gastrointestinal (GI) wall, mesentery, omentum or retroperitoneum that express the c-kit proto-oncogene protein [1].
Gene_expression (express) of proto-oncogene protein in mesentery associated with cancer and gastrointestinal stromal tumor
5) Confidence 0.02 Published 2005 Journal World J Surg Oncol Section Body Doc Link PMC549541 Disease Relevance 1.23 Pain Relevance 0.07

General Comments

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