INT135760

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Context Info
Confidence 0.62
First Reported 2006
Last Reported 2010
Negated 0
Speculated 3
Reported most in Abstract
Documents 2
Total Number 7
Disease Relevance 1.15
Pain Relevance 5.81

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Cyp19a1) endoplasmic reticulum (Cyp19a1) cytoplasm (Cyp19a1)
Anatomy Link Frequency
testis 8
liver 2
brain 2
temporomandibular joint 2
Cyp19a1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Morphine 318 100.00 Very High Very High Very High
Lasting pain 6 100.00 Very High Very High Very High
Snapping jaw 1 99.52 Very High Very High Very High
Opioid 36 95.52 Very High Very High Very High
Pain 114 75.00 Quite High
Analgesic 12 68.80 Quite High
opiate 12 5.00 Very Low Very Low Very Low
Hippocampus 12 5.00 Very Low Very Low Very Low
opioid receptor 12 5.00 Very Low Very Low Very Low
Endogenous opioid 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pain 120 100.00 Very High Very High Very High
Temporomandibular Joint Syndrome 1 99.52 Very High Very High Very High
Cognitive Disorder 18 5.00 Very Low Very Low Very Low
Stress 12 5.00 Very Low Very Low Very Low
Anaemia 6 5.00 Very Low Very Low Very Low
Death 6 5.00 Very Low Very Low Very Low
Fatigue 6 5.00 Very Low Very Low Very Low
Inflammatory Pain 6 5.00 Very Low Very Low Very Low
Reprotox - General 2 6 5.00 Very Low Very Low Very Low
Convulsion 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The effects of age and sex on the expression of aromatase in the rat temporomandibular joint.
Regulation (effects) of Gene_expression (expression) of aromatase in temporomandibular joint associated with snapping jaw
1) Confidence 0.62 Published 2006 Journal J Orofac Pain Section Title Doc Link 16708833 Disease Relevance 0.10 Pain Relevance 0.10
The purpose of this study on male rats was to determine the effects of a single injection of morphine (5 mg/Kg) on persistent pain (formalin test) and the single or combined effects on p450-aromatase and 5-alpha reductase type 1 mRNA expression in the brain, liver and testis.
Regulation (effects) of Gene_expression (expression) of p450-aromatase in testis associated with pain, lasting pain and morphine
2) Confidence 0.17 Published 2010 Journal Mol Pain Section Abstract Doc Link PMC2978140 Disease Relevance 0.17 Pain Relevance 0.95
The purpose of this study on male rats was to determine the effects of a single injection of morphine (5 mg/Kg) on persistent pain (formalin test) and the single or combined effects on p450-aromatase and 5-alpha reductase type 1 mRNA expression in the brain, liver and testis.
Spec (determine) Regulation (effects) of Gene_expression (expression) of p450-aromatase in testis associated with pain, lasting pain and morphine
3) Confidence 0.17 Published 2010 Journal Mol Pain Section Abstract Doc Link PMC2978140 Disease Relevance 0.17 Pain Relevance 0.96
The purpose of this study on male rats was to determine the effects of a single injection of morphine (5 mg/Kg) on persistent pain (formalin test) and the single or combined effects on p450-aromatase and 5-alpha reductase type 1 mRNA expression in the brain, liver and testis.
Regulation (effects) of in liver Gene_expression (expression) of p450-aromatase in testis associated with pain, lasting pain and morphine
4) Confidence 0.06 Published 2010 Journal Mol Pain Section Abstract Doc Link PMC2978140 Disease Relevance 0.17 Pain Relevance 0.95
The purpose of this study on male rats was to determine the effects of a single injection of morphine (5 mg/Kg) on persistent pain (formalin test) and the single or combined effects on p450-aromatase and 5-alpha reductase type 1 mRNA expression in the brain, liver and testis.
Spec (determine) Regulation (effects) of in liver Gene_expression (expression) of p450-aromatase in testis associated with pain, lasting pain and morphine
5) Confidence 0.06 Published 2010 Journal Mol Pain Section Abstract Doc Link PMC2978140 Disease Relevance 0.17 Pain Relevance 0.96
The purpose of this study on male rats was to determine the effects of a single injection of morphine (5 mg/Kg) on persistent pain (formalin test) and the single or combined effects on p450-aromatase and 5-alpha reductase type 1 mRNA expression in the brain, liver and testis.
Regulation (effects) of in brain Gene_expression (expression) of p450-aromatase in testis associated with pain, lasting pain and morphine
6) Confidence 0.06 Published 2010 Journal Mol Pain Section Abstract Doc Link PMC2978140 Disease Relevance 0.17 Pain Relevance 0.95
The purpose of this study on male rats was to determine the effects of a single injection of morphine (5 mg/Kg) on persistent pain (formalin test) and the single or combined effects on p450-aromatase and 5-alpha reductase type 1 mRNA expression in the brain, liver and testis.
Spec (determine) Regulation (effects) of in brain Gene_expression (expression) of p450-aromatase in testis associated with pain, lasting pain and morphine
7) Confidence 0.06 Published 2010 Journal Mol Pain Section Abstract Doc Link PMC2978140 Disease Relevance 0.17 Pain Relevance 0.96

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