INT135820

Context Info Confidence 0.59 First Reported 2006 Last Reported 2006 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 2 Disease Relevance 0 Pain Relevance 1.88

cytosol (Gch1) nucleus (Gch1) protein complex assembly (Gch1) protein complex (Gch1) cytoplasm (Gch1)

Gch1 (Mus musculus)

Pain Link Frequency Relevance Heat lidocaine 20 100.00 tetrodotoxin 8 100.00

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Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The effects of lidocaine on CAT-2 and GTPCH are unknown.

Regulation (effects) of GTPCH associated with lidocaine

1) Confidence 0.59 Published 2006 Journal Anesth. Analg. Section Abstract Doc Link 16717319 Disease Relevance 0 Pain Relevance 0.71

The effects of TTX on iNOS, CAT-2, and GTPCH expression were comparable to those of lidocaine.

Regulation (effects) of GTPCH associated with tetrodotoxin and lidocaine

2) Confidence 0.17 Published 2006 Journal Anesth. Analg. Section Abstract Doc Link 16717319 Disease Relevance 0 Pain Relevance 1.17

General Comments

This test has worked.