INT135953

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Context Info
Confidence 0.37
First Reported 2006
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.09
Pain Relevance 0.37

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Cav1) mitochondrion (Cav1) Golgi apparatus (Cav1)
endoplasmic reticulum (Cav1) intracellular (Cav1) protein complex (Cav1)
Cav1 (Mus musculus)
Pain Link Frequency Relevance Heat
cINOD 6 98.76 Very High Very High Very High
antagonist 5 98.72 Very High Very High Very High
agonist 12 84.16 Quite High
dexamethasone 2 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 7 98.04 Very High Very High Very High
Apoptosis 9 97.68 Very High Very High Very High
Pancreatic Cancer 1 88.64 High High
Cancer 93 86.88 High High
Colon Cancer 6 76.96 Quite High
Breast Cancer 55 59.84 Quite High
Toxicity 5 16.24 Low Low
Metastasis 3 5.00 Very Low Very Low Very Low
Skin Cancer 2 5.00 Very Low Very Low Very Low
Reprotox - General 1 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This was accompanied by loss of caveolin-1 induction but induction of proapoptotic nonsteroidal anti-inflammatory drug activated gene-1.
Negative_regulation (loss) of Positive_regulation (induction) of caveolin-1 associated with inflammation and cinod
1) Confidence 0.37 Published 2006 Journal Mol. Cancer Ther. Section Abstract Doc Link 16731770 Disease Relevance 0.74 Pain Relevance 0.26
Co-treatment of GW9662 inhibited the induction of caveolin-1 and p27 by CDIM9 in MDA-MB231 cells (Figure 2a), suggesting that these responses were PPAR-?
Negative_regulation (inhibited) of Positive_regulation (induction) of caveolin-1
2) Confidence 0.15 Published 2007 Journal Breast Cancer Res Section Body Doc Link PMC2206732 Disease Relevance 0.34 Pain Relevance 0.10

General Comments

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