INT136033

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Context Info
Confidence 0.50
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.34
Pain Relevance 0.95

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Trpv1) extracellular space (Edn1) extracellular region (Edn1)
plasma membrane (Trpv1) lipid metabolic process (Trpv1) cell-cell signaling (Edn1)
Edn1 (Rattus norvegicus)
Trpv1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
qutenza 5 96.84 Very High Very High Very High
Pain 5 96.20 Very High Very High Very High
antagonist 1 86.40 High High
Inflammation 2 76.40 Quite High
dorsal root ganglion 1 75.20 Quite High
nociceptor 1 58.88 Quite High
Disease Link Frequency Relevance Heat
Pain 2 96.20 Very High Very High Very High
Ganglion Cysts 1 75.20 Quite High
INFLAMMATION 2 71.00 Quite High
Cancer 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The data indicate that ET-1 potentiates TRPV1 activity via the ET(A) receptor and that this process is likely to play a crucial role in the pain-producing and pain-potentiating effects of ET-1.
ET-1 Positive_regulation (potentiates) of TRPV1 associated with pain
1) Confidence 0.50 Published 2006 Journal Exp. Biol. Med. (Maywood) Section Abstract Doc Link 16741069 Disease Relevance 0.34 Pain Relevance 0.95

General Comments

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