INT136044

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Context Info
Confidence 0.78
First Reported 2006
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 7
Total Number 7
Disease Relevance 0.19
Pain Relevance 1.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Rock2) cytoskeleton (Rock2) nucleus (Rock2)
kinase activity (Rock2) cytoplasm (Rock2)
Anatomy Link Frequency
spinal cord 3
brain 3
Rock2 (Mus musculus)
Pain Link Frequency Relevance Heat
Spinal cord 12 99.54 Very High Very High Very High
tetrodotoxin 1 92.36 High High
conotoxin 1 91.68 High High
Antinociceptive 18 89.56 High High
Pain 18 25.00 Low Low
Analgesic 6 25.00 Low Low
Disease Link Frequency Relevance Heat
Nociception 6 95.20 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, the expression of Rho-kinase protein (ROCK-2) was studied in the mouse brain and spinal cord by Western blotting.
Gene_expression (expression) of Rho-kinase protein in spinal cord associated with spinal cord
1) Confidence 0.78 Published 2006 Journal Eur. J. Pharmacol. Section Abstract Doc Link 16750189 Disease Relevance 0 Pain Relevance 0.13
Western blot analysis revealed that mouse spinal cord and brain homogenates expressed ROCK-2 protein.
Gene_expression (expressed) of ROCK-2 protein in brain associated with spinal cord
2) Confidence 0.78 Published 2006 Journal Eur. J. Pharmacol. Section Abstract Doc Link 16750189 Disease Relevance 0.10 Pain Relevance 0.20
In addition, the expression of Rho-kinase protein (ROCK-2) was studied in the mouse brain and spinal cord by Western blotting.
Gene_expression (expression) of ROCK-2 in spinal cord associated with spinal cord
3) Confidence 0.78 Published 2006 Journal Eur. J. Pharmacol. Section Abstract Doc Link 16750189 Disease Relevance 0 Pain Relevance 0.13
The myosin light chain phosphatase (MLCP) inhibitor calyculin-A reduced the NaHS-induced relaxation, but the Rho-kinase inhibitor Y-27632 had no influence.
Gene_expression (reduced) of Rho-kinase
4) Confidence 0.43 Published 2009 Journal Eur. J. Pharmacol. Section Abstract Doc Link 19374871 Disease Relevance 0 Pain Relevance 0.14
In addition, the expression of Rho-kinase protein (ROCK-2) was studied in the mouse brain and spinal cord by Western blotting.
Gene_expression (expression) of Rho-kinase protein in brain associated with spinal cord
5) Confidence 0.26 Published 2006 Journal Eur. J. Pharmacol. Section Abstract Doc Link 16750189 Disease Relevance 0 Pain Relevance 0.13
In addition, the expression of Rho-kinase protein (ROCK-2) was studied in the mouse brain and spinal cord by Western blotting.
Gene_expression (expression) of ROCK-2 in brain associated with spinal cord
6) Confidence 0.26 Published 2006 Journal Eur. J. Pharmacol. Section Abstract Doc Link 16750189 Disease Relevance 0 Pain Relevance 0.13
Western blot analysis revealed that mouse spinal cord and brain homogenates expressed ROCK-2 protein.
Gene_expression (expressed) of ROCK-2 protein in spinal cord associated with spinal cord
7) Confidence 0.26 Published 2006 Journal Eur. J. Pharmacol. Section Abstract Doc Link 16750189 Disease Relevance 0.10 Pain Relevance 0.20

General Comments

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