INT136102

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.70
First Reported 2006
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 3.21
Pain Relevance 0.59

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (ALK) signal transduction (ALK) plasma membrane (ALK)
Anatomy Link Frequency
urinary bladder 2
ALK (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 7 98.92 Very High Very High Very High
Pain 1 98.28 Very High Very High Very High
imagery 2 96.92 Very High Very High Very High
positron emission tomography 1 90.00 High High
Angina 1 78.16 Quite High
antagonist 1 50.16 Quite High
chemokine 5 5.00 Very Low Very Low Very Low
corticosteroid 3 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
Spinal cord 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Lymphatic System Cancer 124 100.00 Very High Very High Very High
Cancer 51 99.68 Very High Very High Very High
INFLAMMATION 7 98.92 Very High Very High Very High
Anaplastic Large Cell Lymphoma 20 98.70 Very High Very High Very High
Pain 1 98.28 Very High Very High Very High
Overactive Bladder 1 97.96 Very High Very High Very High
Metastasis 2 90.96 High High
Syndrome 6 87.76 High High
Carcinoma 1 84.28 Quite High
Malignant Neoplastic Disease 8 80.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Immunohistochemical staining also showed an overexpression of ALK in the tumor.
Positive_regulation (overexpression) of Gene_expression (overexpression) of ALK associated with cancer
1) Confidence 0.70 Published 2009 Journal Nihon Kokyuki Gakkai Zasshi Section Abstract Doc Link 20058697 Disease Relevance 1.09 Pain Relevance 0.33
[A case of inflammatory myofibroblastic tumor of the urinary bladder finally diagnosed by anaplastic lymphoma kinase (ALK) immunostaining].
Positive_regulation (diagnosed) of Gene_expression (immunostaining) of ALK in urinary bladder associated with lymphatic system cancer, inflammation and cancer
2) Confidence 0.49 Published 2006 Journal Hinyokika Kiyo Section Title Doc Link 16758729 Disease Relevance 0.83 Pain Relevance 0.23
Nucleophosmin (NPM)-ALK, the characteristic fusion gene oncoprotein expressed in ALK(+)ALCL, directly contributes to the aberrant expression of IL-22R1, as transfection of NPM-ALK in Jurkat cells induced IL-22R1 expression and IL-22-mediated STAT3 activation [18].
Positive_regulation (transfection) of Gene_expression (transfection) of NPM-ALK associated with anaplastic large cell lymphoma
3) Confidence 0.08 Published 2008 Journal J Hematop Section Body Doc Link PMC2713479 Disease Relevance 1.29 Pain Relevance 0.03

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox