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Context Info
Confidence 0.60
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.56
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

oxidoreductase activity (Hsd11b1) endoplasmic reticulum (Hsd11b1) lipid metabolic process (Hsd11b1)
cytoplasm (Hsd11b1)
Anatomy Link Frequency
fat 2
Hsd11b1 (Mus musculus)
Pain Link Frequency Relevance Heat
cocaine 1 68.00 Quite High
Opioid 2 25.00 Low Low
narcan 1 25.00 Low Low
Endogenous opioid 1 25.00 Low Low
MU agonist 1 25.00 Low Low
antagonist 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Obesity 1 99.84 Very High Very High Very High
Hyperphagia 5 98.96 Very High Very High Very High
Metabolic Syndrome 1 98.16 Very High Very High Very High
Metabolic Disorder 1 95.24 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Although overexpression of 11 beta-HSD1 in adipose tissue causes hyperphagia and the metabolic syndrome, male 11 beta-HSD1 null (11 beta-HSD1-/-) mice resist metabolic disease on high-fat (HF) diet, but also show hyperphagia.
Positive_regulation (overexpression) of Gene_expression (overexpression) of beta-HSD1 in fat associated with hyperphagia, metabolic disorder, obesity and metabolic syndrome
1) Confidence 0.60 Published 2006 Journal Endocrinology Section Abstract Doc Link 16763061 Disease Relevance 0.56 Pain Relevance 0.03

General Comments

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