INT136246

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Context Info
Confidence 0.05
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.22
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Gucy1a2, Nppa) cytosol (Gucy1a2) extracellular region (Nppa)
nucleus (Nppa)
Gucy1a2 (Rattus norvegicus)
Nppa (Rattus norvegicus)
Pain Link Frequency Relevance Heat
antagonist 1 100.00 Very High Very High Very High
agonist 2 89.44 High High
Clonidine 2 65.68 Quite High
Central nervous system 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Natriuresis 2 78.64 Quite High
Heart Rate Under Development 1 62.80 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
ANP release stimulated by moxonidine (10(-6) M) was inhibited by co-perfusion with the antagonists, AGN192403 (imidazoline I1-receptor), phenoxybenzamine (alpha2>alpha1-adrenoceptors), and prazosin (alpha1>alpha2-adrenoceptors), but increased by rauwolscine (alpha2-adrenoceptors).
alpha2 Negative_regulation (inhibited) of ANP associated with antagonist
1) Confidence 0.05 Published 2006 Journal Eur. J. Pharmacol. Section Abstract Doc Link 16774751 Disease Relevance 0.22 Pain Relevance 0.26

General Comments

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