INT136280

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Context Info
Confidence 0.67
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 1.13
Pain Relevance 0.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (GAPDH) small molecule metabolic process (GAPDH) oxidoreductase activity (GAPDH)
nucleus (GAPDH) carbohydrate metabolic process (GAPDH) cytoplasm (GAPDH)
Anatomy Link Frequency
blood 2
GAPDH (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 15 99.06 Very High Very High Very High
metalloproteinase 15 96.28 Very High Very High Very High
Inflammation 26 82.04 Quite High
qutenza 1 75.00 Quite High
depression 1 54.16 Quite High
agonist 1 50.00 Quite Low
imagery 6 33.08 Quite Low
Immobilon 1 13.76 Low Low
Central nervous system 1 7.76 Low Low
Inflammatory response 7 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 22 87.92 High High
INFLAMMATION 35 82.04 Quite High
Myopia 22 73.12 Quite High
Hyperopia 9 72.24 Quite High
Leukemia 1 61.48 Quite High
Injury 8 60.68 Quite High
Pathologic Constriction 5 60.28 Quite High
Schizophrenia 1 54.76 Quite High
Depression 1 54.16 Quite High
Diabetes Mellitus 73 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Using qRT-PCR, TRPV2 mRNA was highly expressed in human whole blood isolates (9.33+/-1.19 x 10(4)copies per 10(6)copies of the housekeeping gene GAPDH), whereas TRPV1 message was detected at approximately 150-fold lower levels (638+/-121 copies per 10(6)copies GAPDH).
Transcription (detected) of GAPDH in blood
1) Confidence 0.67 Published 2007 Journal Mol. Immunol. Section Abstract Doc Link 16777226 Disease Relevance 0 Pain Relevance 0.07
Cytokine mRNA levels were analyzed by normalizing with GAPDH mRNA expression.
Transcription (expression) of GAPDH associated with cytokine
2) Confidence 0.52 Published 2007 Journal Cardiovasc Diabetol Section Body Doc Link PMC1892541 Disease Relevance 0.34 Pain Relevance 0.13
However, as Figure 1 shows, when the BDNF mRNA level in blood from eight control participants was normalized to glyceraldehyde-3-phosphate dehydrogenase (GAPDH) mRNA or ?
Transcription (normalized) of glyceraldehyde-3-phosphate in blood
3) Confidence 0.11 Published 2010 Journal Genome Biol Section Body Doc Link PMC2847721 Disease Relevance 0.41 Pain Relevance 0.03
Target gene expression was normalized to glyceraldehyde 3-phosphate dehydrogenase (GAPDH) mRNA expression and reported as mean copies ± standard deviation of target gene mRNA per copy of GAPDH mRNA.
Transcription (expression) of glyceraldehyde 3-phosphate
4) Confidence 0.04 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2656243 Disease Relevance 0.06 Pain Relevance 0.05
A comparison between both lists is difficult because the authors had constructed their own microarrays and had normalized the data against the expression of glyceraldehyde-3-phosphate dehydrogenase mRNA.
Transcription (expression) of glyceraldehyde-3-phosphate
5) Confidence 0.01 Published 2008 Journal Molecular Vision Section Body Doc Link PMC2528026 Disease Relevance 0.32 Pain Relevance 0

General Comments

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