INT136286

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Context Info
Confidence 0.75
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 4
Disease Relevance 1.36
Pain Relevance 1.34

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
lamina 1
primary sensory neurons 1
dorsal root ganglia 1
Synpr (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Root ganglion neuron 16 99.98 Very High Very High Very High
Calcitonin gene-related peptide 4 98.04 Very High Very High Very High
Peripheral nerve injury 8 96.56 Very High Very High Very High
Spinal cord 4 93.24 High High
spinal dorsal horn 4 89.20 High High
Adelta 4 64.80 Quite High
c fibre 4 63.84 Quite High
Neuropathic pain 4 61.04 Quite High
Disease Link Frequency Relevance Heat
Ganglion Cysts 16 99.82 Very High Very High Very High
Nervous System Injury 8 96.12 Very High Very High Very High
Neuropathic Pain 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, a subpopulation of isolectin B4-positive small dorsal root ganglion neurons expressed both synaptoporin and synaptophysin, and their afferent fibers were mainly distributed in the ventral part of inner lamina II.
Gene_expression (expressed) of synaptoporin in lamina associated with ganglion cysts and root ganglion neuron
1) Confidence 0.75 Published 2006 Journal Neuroscience Section Abstract Doc Link 16777346 Disease Relevance 0.52 Pain Relevance 0.54
In the present study, we showed that in the rat dorsal root ganglia synaptoporin was expressed in subsets of small neurons that contain either calcitonin gene-related peptide or isolectin B4, and was distributed in their afferent terminals in laminae I-II of the spinal cord.
Gene_expression (expressed) of synaptoporin in dorsal root ganglia associated with spinal cord and calcitonin gene-related peptide
2) Confidence 0.75 Published 2006 Journal Neuroscience Section Abstract Doc Link 16777346 Disease Relevance 0.28 Pain Relevance 0.27
Differential expression of synaptoporin and synaptophysin in primary sensory neurons and up-regulation of synaptoporin after peripheral nerve injury.
Gene_expression (expression) of synaptoporin in primary sensory neurons associated with nervous system injury and peripheral nerve injury
3) Confidence 0.75 Published 2006 Journal Neuroscience Section Title Doc Link 16777346 Disease Relevance 0.35 Pain Relevance 0.32
The distribution of synaptoporin and its relationship with synaptophysin in sensory afferent fibers remain unclear.
Gene_expression (distribution) of synaptoporin
4) Confidence 0.65 Published 2006 Journal Neuroscience Section Abstract Doc Link 16777346 Disease Relevance 0.20 Pain Relevance 0.21

General Comments

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