INT136335

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Context Info
Confidence 0.11
First Reported 2005
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 1.53
Pain Relevance 2.54

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Mmp10) extracellular region (Mmp10) proteinaceous extracellular matrix (Mmp10)
Mmp10 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
trigeminal ganglion 12 99.16 Very High Very High Very High
neuropeptide release 4 97.40 Very High Very High Very High
nociceptor 16 94.72 High High
agonist 8 91.28 High High
Face pain 2 90.64 High High
opioid receptor 16 87.52 High High
qutenza 2 82.76 Quite High
metalloproteinase 12 74.56 Quite High
Pain 2 74.00 Quite High
cytokine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 12 99.16 Very High Very High Very High
Adhesions 17 92.64 High High
Facial Pain 2 90.64 High High
Cv General 3 Under Development 1 81.76 Quite High
Myocardial Infarction 2 80.28 Quite High
Nociception 2 76.04 Quite High
Coronary Artery Disease 1 50.00 Quite Low
Pulmonary Hypertension 35 26.24 Quite Low
Congenital Anomalies 3 12.64 Low Low
Injury 2 5.28 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, the stromelysins MMP 10, MMP 11, MMP 12 and MMP 20 were significantly upregulated by factors of 4.65 ± 1.13, 5.27 ± 1.03, 2.27 ± 0.63 and 6.67 ± 0.75, respectively.
Regulation (upregulated) of MMP 10
1) Confidence 0.11 Published 2005 Journal Respir Res Section Body Doc Link PMC1291406 Disease Relevance 0.36 Pain Relevance 0.04
In cultures treated with siRNA against PAR-2, both SL-NH2 and trypsin responses were significantly diminished.
Regulation (responses) of SL-NH2
2) Confidence 0.05 Published 2006 Journal Pain Section Abstract Doc Link 16781076 Disease Relevance 0.50 Pain Relevance 1.40
Serum levels of pro-MMP1, MMP2, MMP3, MMP9, and MMP10 were measured in 199 randomly selected patients from each group.
Regulation (measured) of MMP10
3) Confidence 0.03 Published 2007 Journal Am. Heart J. Section Body Doc Link 18035073 Disease Relevance 0.16 Pain Relevance 0
The specificity of SL-NH2 and trypsin responses was evaluated using TG cultures transfected with siRNA against PAR-2.
Regulation (responses) of SL-NH2 associated with trigeminal ganglion
4) Confidence 0.03 Published 2006 Journal Pain Section Abstract Doc Link 16781076 Disease Relevance 0.51 Pain Relevance 1.11

General Comments

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