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Context Info
Confidence 0.07
First Reported 2006
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 4
Disease Relevance 1.05
Pain Relevance 1.75

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Mmp10) extracellular region (Mmp10) proteinaceous extracellular matrix (Mmp10)
Anatomy Link Frequency
nociceptor 1
Mmp10 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
metalloproteinase 4 100.00 Very High Very High Very High
Face pain 1 99.08 Very High Very High Very High
opioid receptor 8 98.96 Very High Very High Very High
nociceptor 8 98.20 Very High Very High Very High
chemokine 6 94.76 High High
cytokine 20 94.28 High High
Inflammation 40 93.88 High High
trigeminal ganglion 6 90.40 High High
Pain 7 88.16 High High
neuropeptide release 2 81.60 Quite High
Disease Link Frequency Relevance Heat
Facial Pain 1 99.08 Very High Very High Very High
INFLAMMATION 44 93.88 High High
Arthritis 22 88.24 High High
Ganglion Cysts 6 85.68 High High
Cv General 3 Under Development 1 83.44 Quite High
Myocardial Infarction 2 81.96 Quite High
Osteoarthritis 46 78.08 Quite High
Coronary Artery Disease 1 50.00 Quite Low
Nociception 1 42.80 Quite Low
Pain 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Serum levels of pro-MMP1, MMP2, MMP3, MMP9, and MMP10 were measured in 199 randomly selected patients from each group.
Gene_expression (levels) of MMP10
1) Confidence 0.07 Published 2007 Journal Am. Heart J. Section Body Doc Link 18035073 Disease Relevance 0.17 Pain Relevance 0
By increasing the expression of matrix metalloproteinases (MMP-3, MMP-9, MMP-10, MMP-12, and MMP-13) while inhibiting the expression of genes encoding essential components of the ECM (such as collagen type II and aggrecan-1), the elevated IL-1?
Gene_expression (expression) of MMP-10 associated with metalloproteinase
2) Confidence 0.06 Published 2006 Journal Arthritis Res Ther Section Body Doc Link PMC1794517 Disease Relevance 0.20 Pain Relevance 0.30
It also blocked the IL-1-induced expression of matrix-specific proteases such as MMP-3, MMP-9, MMP-10, MMP-12, and ADAMTS-1.
Gene_expression (expression) of MMP-10
3) Confidence 0.06 Published 2006 Journal Arthritis Res Ther Section Abstract Doc Link PMC1794517 Disease Relevance 0.26 Pain Relevance 0.18
Application of SL-NH2 rapidly produced functional competence of DOR for inhibiting nociceptor function.
Gene_expression (produced) of SL-NH2 in nociceptor associated with nociceptor and opioid receptor
4) Confidence 0.05 Published 2006 Journal Pain Section Abstract Doc Link 16781076 Disease Relevance 0.43 Pain Relevance 1.27

General Comments

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