INT136494

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Context Info
Confidence 0.08
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.77
Pain Relevance 0.77

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Ltb4r) plasma membrane (Ltb4r) signal transducer activity (Ltb4r)
Anatomy Link Frequency
joints 2
lung 2
Ltb4r (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 46 99.40 Very High Very High Very High
Arthritis 2 90.96 High High
narcan 2 78.32 Quite High
Antinociceptive 2 76.00 Quite High
Pain 5 75.00 Quite High
cytokine 10 74.88 Quite High
antagonist 1 71.52 Quite High
opioid receptor 1 71.08 Quite High
Inflammatory mediators 5 66.04 Quite High
Endogenous opioid 1 52.80 Quite High
Disease Link Frequency Relevance Heat
Pneumonia 21 99.40 Very High Very High Very High
INFLAMMATION 29 97.96 Very High Very High Very High
Hypersensitivity 86 91.88 High High
Arthritis 2 90.96 High High
Nociception 4 79.16 Quite High
Pain 2 75.00 Quite High
Hemorrhagic Shock 1 59.72 Quite High
Asthma 24 53.68 Quite High
Necrosis 2 52.48 Quite High
Cancer 2 52.12 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Risedronate, at 50 and 100 microg/kg, significantly inhibited LTB4 release into the joints compared with the NT group (2883.1 +/- 73.2, 1911.5 +/- 205.3 and 4709.9 +/- 237.2 pg/mL, respectively).
Negative_regulation (inhibited) of Localization (release) of LTB4 in joints
1) Confidence 0.08 Published 2006 Journal Clin. Exp. Pharmacol. Physiol. Section Abstract Doc Link 16789926 Disease Relevance 0.71 Pain Relevance 0.47
In parallel, LTB4 release by lung cells was prevented by estradiol and progesterone.
Negative_regulation (prevented) of Localization (release) of LTB4 in lung
2) Confidence 0.04 Published 2010 Journal Respir Res Section Body Doc Link PMC2936382 Disease Relevance 1.06 Pain Relevance 0.30

General Comments

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