INT136531

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Context Info
Confidence 0.47
First Reported 2005
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 8
Total Number 8
Disease Relevance 9.62
Pain Relevance 0.65

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein binding, bridging (Men1) embryo development (Men1) DNA binding (Men1)
protein complex (Men1) cytoplasm (Men1) cytosol (Men1)
Anatomy Link Frequency
pancreas 1
pituitary 1
adrenal gland 1
parathyroid 1
Men1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
peptic ulcer disease 10 93.36 High High
imagery 29 91.72 High High
headache 1 70.40 Quite High
abdominal pain 7 26.52 Quite Low
Central nervous system 8 5.00 Very Low Very Low Very Low
Angina 4 5.00 Very Low Very Low Very Low
ischemia 4 5.00 Very Low Very Low Very Low
medulla 4 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Syndrome 85 100.00 Very High Very High Very High
Multiple Endocrine Neoplasia Type 1 52 100.00 Very High Very High Very High
Insulinoma 8 99.98 Very High Very High Very High
Gastrinoma 83 99.76 Very High Very High Very High
Carcinoid 32 99.58 Very High Very High Very High
Recurrence 11 97.12 Very High Very High Very High
Cancer 74 95.88 Very High Very High Very High
Diarrhoea 19 95.64 Very High Very High Very High
Pancreatic Cancer 6 95.56 Very High Very High Very High
Gastroesophageal Reflux Disease 9 94.68 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The diagnosis and surgical management of insulinomas associated with multiple endocrine neoplasia type 1 (MEN1) pose additional problems in children because of the long-term risk of recurrence of other pancreatic and non-pancreatic tumors.
MEN1 Binding (associated) of associated with multiple endocrine neoplasia type 1, pancreatic cancer, insulinoma and recurrence
1) Confidence 0.47 Published 2006 Journal J Laparoendosc Adv Surg Tech A Section Abstract Doc Link 16796455 Disease Relevance 1.03 Pain Relevance 0.10
The duodenal gastrinomas are small, and when they occur in association with the genetic syndrome of multiple endocrine neoplasia type 1 (MEN1), they are multicentric and originate from precursor lesions.
MEN1 Binding (association) of associated with multiple endocrine neoplasia type 1, syndrome and gastrinoma
2) Confidence 0.16 Published 2007 Journal Wien. Klin. Wochenschr. Section Abstract Doc Link 17985091 Disease Relevance 1.38 Pain Relevance 0.09
It should be mentioned that carcinoid is not infrequently associated with MEN1 and loss of 11q, sometimes independently of the MEN1 gene (11q13), suggesting loss of MEN1 or another tumour suppressor gene is responsible for the condition.
MEN1 Binding (associated) of associated with multiple endocrine neoplasia type 1, carcinoid and cancer
3) Confidence 0.12 Published 2008 Journal Cases J Section Body Doc Link PMC2546371 Disease Relevance 2.20 Pain Relevance 0
The association with MEN1 status was evaluated by hormonal and radiologic investigations of the parathyroid, pituitary, pancreas, and adrenal gland, which proved to be negative.
MEN1 Binding (association) of in pituitary associated with multiple endocrine neoplasia type 1
4) Confidence 0.10 Published 2005 Journal BMC Cancer Section Body Doc Link PMC1181810 Disease Relevance 0.71 Pain Relevance 0.09
Genetically, nonhereditary (sporadic) gastrinomas are distinguished from hereditary gastrinomas, which are associated with multiple endocrine neoplasia type 1 (MEN1) syndrome.
MEN1 Binding (associated) of associated with multiple endocrine neoplasia type 1, syndrome and gastrinoma
5) Confidence 0.10 Published 2006 Journal World J. Gastroenterol. Section Abstract Doc Link 17006979 Disease Relevance 2.17 Pain Relevance 0.09
The association with MEN1 status was evaluated by hormonal and radiologic investigations of the parathyroid, pituitary, pancreas, and adrenal gland, which proved to be negative.
MEN1 Binding (association) of in adrenal gland associated with multiple endocrine neoplasia type 1
6) Confidence 0.04 Published 2005 Journal BMC Cancer Section Body Doc Link PMC1181810 Disease Relevance 0.71 Pain Relevance 0.09
The association with MEN1 status was evaluated by hormonal and radiologic investigations of the parathyroid, pituitary, pancreas, and adrenal gland, which proved to be negative.
MEN1 Binding (association) of in parathyroid associated with multiple endocrine neoplasia type 1
7) Confidence 0.04 Published 2005 Journal BMC Cancer Section Body Doc Link PMC1181810 Disease Relevance 0.71 Pain Relevance 0.09
The association with MEN1 status was evaluated by hormonal and radiologic investigations of the parathyroid, pituitary, pancreas, and adrenal gland, which proved to be negative.
MEN1 Binding (association) of in pancreas associated with multiple endocrine neoplasia type 1
8) Confidence 0.04 Published 2005 Journal BMC Cancer Section Body Doc Link PMC1181810 Disease Relevance 0.71 Pain Relevance 0.09

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