INT13654

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Context Info
Confidence 0.44
First Reported 1991
Last Reported 2006
Negated 0
Speculated 1
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.44
Pain Relevance 0.68

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (SLC2A1) plasma membrane (SLC2A1) intracellular (SLC2A1)
carbohydrate metabolic process (SLC2A1) transmembrane transport (SLC2A1) cytoplasm (SLC2A1)
Anatomy Link Frequency
skin 1
SLC2A1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Glutamate 4 100.00 Very High Very High Very High
nMDA receptor antagonist 1 97.20 Very High Very High Very High
Spinal cord 1 96.60 Very High Very High Very High
spinothalamic tract 3 94.00 High High
excitatory amino acid 5 93.64 High High
spinothalamic 1 75.00 Quite High
antagonist 1 75.00 Quite High
Neuropeptide 1 51.76 Quite High
Hyperalgesia 1 49.20 Quite Low
Dismenorea 2 43.20 Quite Low
Disease Link Frequency Relevance Heat
Nociception 1 94.80 High High
Endometriosis (extended) 4 75.00 Quite High
Endometrial Hyperplasia 1 75.00 Quite High
Malignant Neoplastic Disease 4 73.92 Quite High
Hyperplasia 10 61.52 Quite High
Dysmenorrhea 2 43.20 Quite Low
Adenocarcinoma 3 32.48 Quite Low
Cancer 2 25.00 Low Low
Hypoxia 1 25.00 Low Low
Hyperalgesia 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the present study, the microiontophoresis technique was used to investigate the effects of L-glutamate (GLUT), N-methyl-D-aspartate (NMDA), and quisqualate (QUIS), as well as an NMDA receptor antagonist, AP-7, on the discharges evoked in nociceptive primate spinothalamic tract (STT) neurons by mechanical stimulation of the skin.
Spec (investigate) Regulation (effects) of GLUT in skin associated with nociception, spinothalamic tract, nmda receptor antagonist and glutamate
1) Confidence 0.44 Published 1991 Journal Brain Res. Section Abstract Doc Link 1675920 Disease Relevance 0.09 Pain Relevance 0.68
The facilitative transport of monosaccharides in human cells is accomplished by a family of transmembrane proteins, GLUT-1 to GLUT-7, that differ in their tissue distribution, affinities for specific monosaccharides, and physiologic regulation.
Regulation (regulation) of GLUT-1
2) Confidence 0.27 Published 2006 Journal Appl. Immunohistochem. Mol. Morphol. Section Abstract Doc Link 16785788 Disease Relevance 0.34 Pain Relevance 0

General Comments

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