INT136749

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Context Info
Confidence 0.52
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.36
Pain Relevance 0.45

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (COX5A, SCARB1) transport (SCARB1) mitochondrion (COX5A)
cell adhesion (SCARB1) plasma membrane (SCARB1) lipid metabolic process (SCARB1)
Anatomy Link Frequency
macrophages 2
COX5A (Homo sapiens)
SCARB1 (Homo sapiens)
Pain Link Frequency Relevance Heat
aspirin 9 100.00 Very High Very High Very High
cOX1 1 87.20 High High
cINOD 1 66.48 Quite High
Disease Link Frequency Relevance Heat
Targeted Disruption 1 94.12 High High
Disorder Of Lipid Metabolism 1 75.80 Quite High
Sprains And Strains 1 70.52 Quite High
Increased Venous Pressure Under Development 1 62.28 Quite High
Atherosclerotic Plaque 1 59.88 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We could show that COX-independent effects of aspirin were able to enhance expression of SR-BI in macrophages in a post-transcriptional, PPAR-alpha independent way, suggesting a novel pharmacologic effect of aspirin.
COX Positive_regulation (enhance) of Gene_expression (expression) of SR-BI in macrophages associated with aspirin
1) Confidence 0.52 Published 2006 Journal FASEB J. Section Abstract Doc Link 16816107 Disease Relevance 0.36 Pain Relevance 0.45

General Comments

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