INT136750

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Context Info
Confidence 0.65
First Reported 2006
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.48
Pain Relevance 0.43

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (SCARF1)
Anatomy Link Frequency
blood 1
macrophages 1
livers 1
SCARF1 (Homo sapiens)
Pain Link Frequency Relevance Heat
aspirin 10 99.78 Very High Very High Very High
cINOD 1 86.80 High High
cOX1 1 66.00 Quite High
Inflammation 10 50.00 Quite Low
Angina 2 28.72 Quite Low
Bile 3 5.16 Low Low
fibrosis 10 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
depression 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Myocardial Infarction 22 99.76 Very High Very High Very High
Cirrhosis 110 98.72 Very High Very High Very High
Fibrosis 8 95.56 Very High Very High Very High
Atherosclerotic Plaque 1 94.04 High High
Increased Venous Pressure Under Development 2 91.36 High High
Sprains And Strains 2 82.80 Quite High
Disorder Of Lipid Metabolism 1 77.36 Quite High
Cardiovascular Disease 1 63.88 Quite High
Targeted Disruption 1 59.24 Quite High
INFLAMMATION 11 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
All SCARF participants were below the age of 60 and blood sampling was performed 3 months after the index cardiac event.
Gene_expression (participants) of SCARF in blood
1) Confidence 0.65 Published 2008 Journal Heart Section Body Doc Link PMC2564840 Disease Relevance 0.34 Pain Relevance 0
Aspirin regulates expression and function of scavenger receptor-BI in macrophages: studies in primary human macrophages and in mice.
Gene_expression (expression) of scavenger receptor-BI in macrophages associated with aspirin
2) Confidence 0.06 Published 2006 Journal FASEB J. Section Title Doc Link 16816107 Disease Relevance 0.40 Pain Relevance 0.43
The expression of a scavenger receptor class B, CD36, was reported on HSC and a co-localisation with alpha-smooth muscle actin-positive HSC in human fibrotic livers was immunohistochemically demonstrated (30).
Gene_expression (expression) of scavenger receptor in livers associated with fibrosis and cirrhosis
3) Confidence 0.02 Published 2007 Journal Pharm Res Section Body Doc Link PMC1915609 Disease Relevance 0.74 Pain Relevance 0

General Comments

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