INT136922

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Context Info
Confidence 0.46
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.28
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (DLL1) extracellular region (DLL1) plasma membrane (DLL1)
cell-cell signaling (DLL1)
Anatomy Link Frequency
lateral 2
DLL1 (Homo sapiens)
Pain Link Frequency Relevance Heat
tetrodotoxin 1 96.16 Very High Very High Very High
sodium channel 1 73.48 Quite High
beta blocker 1 5.00 Very Low Very Low Very Low
drug abuse 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
antiepileptic Drug 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pressure And Volume Under Development 2 99.92 Very High Very High Very High
Hypertension 4 99.84 Very High Very High Very High
Diabetes Mellitus 6 96.24 Very High Very High Very High
Reprotox - General 1 4 75.72 Quite High
Renal Insufficiency 1 74.80 Quite High
Heart Disease 1 70.16 Quite High
Death 2 63.52 Quite High
Atherosclerosis 2 62.88 Quite High
Uremia 5 61.36 Quite High
Calcification 34 58.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Importantly, decreasing Dll1 expression increased the lateral motility of PC-3 cells, whereas blocking voltage-gated Na(+) channel activity with tetrodotoxin decreased motility.
Positive_regulation (increased) of Gene_expression (expression) of Dll1 in lateral associated with tetrodotoxin
1) Confidence 0.46 Published 2006 Journal Prostate Cancer Prostatic Dis. Section Abstract Doc Link 16832382 Disease Relevance 0.29 Pain Relevance 0.13
Delta Agatston score was significantly higher in hypertensive (p < 0.020) compared to non hypertensive HD patients

Discussion

Positive_regulation (higher) of Gene_expression (score) of Delta associated with hypertension
2) Confidence 0.08 Published 2010 Journal BMC Nephrol Section Body Doc Link PMC2903573 Disease Relevance 0.98 Pain Relevance 0

General Comments

This test has worked.

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