INT136989

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Context Info
Confidence 0.04
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.09
Pain Relevance 1.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (EGF, KCNJ2) signal transduction (EGF) extracellular space (EGF)
extracellular region (EGF)
Anatomy Link Frequency
BUC 2
EGF (Homo sapiens)
KCNJ2 (Homo sapiens)
Pain Link Frequency Relevance Heat
interstitial cystitis 12 100.00 Very High Very High Very High
cytokine 1 79.08 Quite High
Hyperalgesia 1 77.92 Quite High
Disease Link Frequency Relevance Heat
Interstitial Cystitis 12 100.00 Very High Very High Very High
Congenital Anomalies 1 80.64 Quite High
Hyperalgesia 1 77.92 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
EGF is secreted in higher amounts by IC BUC and is known to decrease Kir2.1 conductance by phosphorylation of Kir2.1.
EGF Negative_regulation (decrease) of Positive_regulation (conductance) of Kir2 in BUC associated with interstitial cystitis
1) Confidence 0.04 Published 2007 Journal Am. J. Physiol., Cell Physiol. Section Abstract Doc Link 16837648 Disease Relevance 1.09 Pain Relevance 1.10

General Comments

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