INT137162

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Context Info
Confidence 0.45
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.62
Pain Relevance 0.54

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IFNG, CXCL9) extracellular region (IFNG, CXCL9) signal transduction (CXCL9)
cell-cell signaling (CXCL9)
IFNG (Homo sapiens)
CXCL9 (Homo sapiens)
Pain Link Frequency Relevance Heat
Etanercept 1 98.02 Very High Very High Very High
chemokine 6 93.84 High High
spinal inflammation 1 79.04 Quite High
Arthritis 5 76.16 Quite High
rheumatoid arthritis 1 75.04 Quite High
cytokine 1 75.00 Quite High
Disease Link Frequency Relevance Heat
Necrosis 1 86.84 High High
Cancer 1 86.48 High High
Spondylarthropathies 1 81.04 Quite High
Low Back Pain 1 79.04 Quite High
Seronegative Spondarthritis 1 76.96 Quite High
Rheumatoid Arthritis 1 75.04 Quite High
Arthritis 4 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Etanercept, a humanized soluble recombinant p75 TNF-receptor/IgG(1)Fc fusionprotein, neutralized synergistic CXCL9 production induced by TNF-alpha plus IFN-gamma, but not synergy between IFN-gamma and the TLR ligands PGN or LPS.
IFN-gamma Positive_regulation (induced) of Gene_expression (production) of CXCL9 associated with etanercept
1) Confidence 0.45 Published 2006 Journal Lab. Invest. Section Abstract Doc Link 16847431 Disease Relevance 0.62 Pain Relevance 0.54

General Comments

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