INT137166

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Context Info
Confidence 0.24
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.28
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (IL8, CXCR2) intracellular (IL8, CXCR2) extracellular space (IL8)
extracellular region (IL8) plasma membrane (CXCR2) signal transducer activity (CXCR2)
Anatomy Link Frequency
endothelial cells 1
IL8 (Homo sapiens)
CXCR2 (Homo sapiens)
Pain Link Frequency Relevance Heat
chemokine 6 100.00 Very High Very High Very High
Arthritis 5 98.36 Very High Very High Very High
cytokine 1 75.00 Quite High
Etanercept 1 33.68 Quite Low
rheumatoid arthritis 1 25.00 Low Low
spinal inflammation 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Arthritis 4 98.36 Very High Very High Very High
Cancer 1 52.40 Quite High
Necrosis 1 51.92 Quite High
Spondylarthropathies 1 25.00 Low Low
Rheumatoid Arthritis 1 25.00 Low Low
Seronegative Spondarthritis 1 25.00 Low Low
Low Back Pain 1 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In contrast to CXC chemokine ligand 8 (CXCL8), no CXC chemokine receptor 3 (CXCR3) ligand (ie CXCL9, CXCL10 and CXCL11) was induced by bacterial TLR ligands in human microvascular endothelial cells (HMVEC).
CXCL8 Positive_regulation (induced) of CXC chemokine receptor 3 in endothelial cells associated with chemokine
1) Confidence 0.24 Published 2006 Journal Lab. Invest. Section Abstract Doc Link 16847431 Disease Relevance 0.28 Pain Relevance 0.27

General Comments

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