INT137204

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Context Info
Confidence 0.70
First Reported 2005
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 6
Disease Relevance 3.86
Pain Relevance 0.67

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (Itgax)
Anatomy Link Frequency
macrophages 1
plaques 1
T cell 1
P-D 1
Itgax (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 58 100.00 Very High Very High Very High
chemokine 5 92.68 High High
pulpitis 1 82.52 Quite High
Multiple sclerosis 2 81.68 Quite High
Spinal cord 1 80.60 Quite High
ischemia 2 80.08 Quite High
Inflammation 28 75.32 Quite High
Inflammatory response 3 68.88 Quite High
Pain 1 62.92 Quite High
Hippocampus 7 23.60 Low Low
Disease Link Frequency Relevance Heat
Disease 71 99.84 Very High Very High Very High
Dental Fissures 1 97.40 Very High Very High Very High
Bites And Stings 5 96.80 Very High Very High Very High
Amyloid Plaque 9 96.16 Very High Very High Very High
Peritonitis 1 89.60 High High
Respiratory Syncytial Virus 62 86.80 High High
Bacterial Infection 1 84.16 Quite High
Infection 56 83.96 Quite High
Epilepsy 1 83.56 Quite High
Pulpitis 1 82.52 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The macrophages from 7-day mucus venom-induced exudates upon in vitro mucus venom stimulation, expressed CD11c x MHC class II and release bioactive IL-12p70.
Localization (release) of CD11c in macrophages
1) Confidence 0.70 Published 2007 Journal Toxicon Section Abstract Doc Link 17321559 Disease Relevance 1.30 Pain Relevance 0.30
Since both CD11c and CD80 are expressed widely on murine APC we asked whether the presence of CD11c on CD8+ T cells is due to expression by T cells rather than to membrane transfer from APC during T cell priming.
Localization (presence) of CD11c in T cell
2) Confidence 0.69 Published 2005 Journal Respir Res Section Body Doc Link PMC1184101 Disease Relevance 0.47 Pain Relevance 0
The presence of MHCII and CD11c labeled cells indicate antigen presentation.
Localization (presence) of CD11c
3) Confidence 0.49 Published 2008 Journal J Neuroinflammation Section Body Doc Link PMC2329612 Disease Relevance 0 Pain Relevance 0.08
CD11c+F4/80- cells were localized in the pulp-dentin (P-D) border of the central pulp beneath the dental fissure, whereas CD11c-F4/80+ cells with dendritic morphology were distributed in the perivascular region of the inner pulp and the sub-odontoblastic layer.
Localization (localized) of CD11c in P-D associated with dental fissures
4) Confidence 0.39 Published 2006 Journal Int. Immunol. Section Abstract Doc Link 16849394 Disease Relevance 0.35 Pain Relevance 0.08
Splenocytes were obtained, stained and analyzed by FACS to evaluate lymphoid DCs (CD11c+ CD8?
Localization (evaluate) of CD11c
5) Confidence 0.36 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2776531 Disease Relevance 0 Pain Relevance 0
Among them, complement proteins, from the initial component C1q through the terminal cytotoxic C5b-C9, the complement receptors CR3 and CR4, and complement inhibitors, cytokines and interleukins (TNF-alpha, IL-1, IL-2, IL-6), and acute phase reactants (alpha1-antichymotrypsin and alpha2-macroglobulin) were exclusively localized in AD plaques.
Localization (localized) of CR4 in plaques associated with disease and cytokine
6) Confidence 0.16 Published 2007 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2654796 Disease Relevance 1.75 Pain Relevance 0.21

General Comments

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