INT137286

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Context Info
Confidence 0.30
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Title
Documents 2
Total Number 2
Disease Relevance 0.56
Pain Relevance 0.75

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

oxidoreductase activity (Vkorc1) endoplasmic reticulum (Vkorc1)
Vkorc1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
induced neuropathy 6 98.92 Very High Very High Very High
Eae 2 97.00 Very High Very High Very High
vincristine 3 88.28 High High
Peripheral nervous system 3 86.08 High High
Central nervous system 1 84.32 Quite High
Opioid 1 72.84 Quite High
Analgesic 2 72.56 Quite High
antidepressant 1 72.08 Quite High
Peripheral nerve injury 1 57.68 Quite High
Spinal cord 1 48.44 Quite Low
Disease Link Frequency Relevance Heat
Neuropathic Pain 6 98.60 Very High Very High Very High
Injury 1 96.16 Very High Very High Very High
Drug Induced Neurotoxicity 2 82.44 Quite High
Nervous System Injury 1 57.24 Quite High
Diabetic Nephropathy 4 56.20 Quite High
Inflammatory Pain 1 55.44 Quite High
Adverse Drug Reaction 6 5.00 Very Low Very Low Very Low
Hemorrhage 5 5.00 Very Low Very Low Very Low
Cv General 3 Under Development 2 5.00 Very Low Very Low Very Low
Thrombosis Related Under Development 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, data generated in a broad warfarin consortium have demonstrated an additive informative value of genetic data on VKORC1 and CYP2C9 even when it is obtained 7–9 days after the start of treatment [35].
Regulation (value) of VKORC1
1) Confidence 0.30 Published 2010 Journal Human Genomics and Proteomics : HGP Section Body Doc Link PMC2958670 Disease Relevance 0 Pain Relevance 0
Involvement of the multidrug resistance transporters in cisplatin-induced neuropathy in rats.
Regulation (Involvement) of resistance associated with induced neuropathy and neuropathic pain
2) Confidence 0.03 Published 2006 Journal Eur. J. Pharmacol. Section Title Doc Link 16859677 Disease Relevance 0.56 Pain Relevance 0.75

General Comments

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