INT137317

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Context Info
Confidence 0.26
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0
Pain Relevance 2.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Rere) nucleus (Rere) DNA binding (Rere)
Rere (Mus musculus)
Pain Link Frequency Relevance Heat
Dynorphin 8 100.00 Very High Very High Very High
Enkephalin 2 100.00 Very High Very High Very High
Antinociceptive 16 99.46 Very High Very High Very High
narcan 4 97.16 Very High Very High Very High
antinociception 6 90.80 High High
Opioid 6 75.04 Quite High
Analgesic 3 25.00 Low Low
ischemia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 20 5.00 Very Low Very Low Very Low
Body Weight 8 5.00 Very Low Very Low Very Low
Hypotension 2 5.00 Very Low Very Low Very Low
INFLAMMATION 2 5.00 Very Low Very Low Very Low
Anorexia 1 5.00 Very Low Very Low Very Low
Dislocations 1 5.00 Very Low Very Low Very Low
Fatigue 1 5.00 Very Low Very Low Very Low
Cv General 4 Under Development 1 5.00 Very Low Very Low Very Low
Diarrhoea 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The antinociceptive effects of both SIN-1 and L-ARG were also blocked to a greater extent by i.c.v. administration of a rabbit antiserum against rat dynorphin 1-13 than an antiserum against methionine-enkephalin, suggesting that the SIN-1 and L-ARG effects may be related to stimulated release of dynorphin.
Localization (release) of L-ARG associated with dynorphin, enkephalin and antinociceptive
1) Confidence 0.26 Published 2006 Journal Brain Res. Bull. Section Abstract Doc Link 16861110 Disease Relevance 0 Pain Relevance 1.13
The antinociceptive effects of both SIN-1 and L-ARG were also blocked to a greater extent by i.c.v. administration of a rabbit antiserum against rat dynorphin 1-13 than an antiserum against methionine-enkephalin, suggesting that the SIN-1 and L-ARG effects may be related to stimulated release of dynorphin.
Localization (release) of L-ARG associated with dynorphin, enkephalin and antinociceptive
2) Confidence 0.12 Published 2006 Journal Brain Res. Bull. Section Abstract Doc Link 16861110 Disease Relevance 0 Pain Relevance 1.06
Seventeen amino acids were determined to be present in the extracts as follows: aspartic acid (Asp), serine (Ser), glutamic acid (Glu), glycine (Gly), alanine (Ala), cysteine (Cys), valine (Val), methionine (Met), isoleucine (Ile), leucine (Leu), tyrosine (Tyr), phenylalanine (Phe), lysine (Lys), asparagines (Asn), histidine (His), arginine (Arg), proline (Pro).
Localization (follows) of Arg
3) Confidence 0.05 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2836181 Disease Relevance 0 Pain Relevance 0

General Comments

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