INT137415

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Context Info
Confidence 0.02
First Reported 2006
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.53
Pain Relevance 0.40

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeletal protein binding (SDC1) small molecule metabolic process (SDC1) extracellular region (SDC1)
plasma membrane (SDC1) protein complex (SDC1) lipid metabolic process (SDC1)
Anatomy Link Frequency
skin 2
SDC1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Crohn's disease 9 99.84 Very High Very High Very High
spastic colon 1 93.76 High High
Inflammation 3 91.44 High High
abdominal pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 9 99.84 Very High Very High Very High
Adhesions 3 98.80 Very High Very High Very High
Malignant Neoplastic Disease 7 98.24 Very High Very High Very High
Cancer 49 95.84 Very High Very High Very High
Functional Bowel Disorder 1 93.76 High High
Skin Cancer 47 92.08 High High
INFLAMMATION 2 91.44 High High
Necrosis 2 88.16 High High
Recurrence 2 79.32 Quite High
Metastasis 10 77.96 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Therefore, our aim in this study was to correlate simultaneous expression of TNFalpha and syndecan-1 in patients affected by CD.
Regulation (affected) of Gene_expression (expression) of syndecan-1 associated with crohn's disease
1) Confidence 0.02 Published 2006 Journal Immunopharmacol Immunotoxicol Section Abstract Doc Link 16873088 Disease Relevance 1.12 Pain Relevance 0.40
Loss of E-cadherin, beta-catenin and altered syndecan-1 expression suggest an impaired cellular adhesion, which may explain the peculiar histological appearance of these tumors and contribute to the observed aggressive clinical behavior in skin, penile and breast ASCC [6,10,12].
Regulation (altered) of Gene_expression (expression) of syndecan-1 in skin associated with cancer, skin cancer and adhesions
2) Confidence 0.00 Published 2011 Journal Diagn Pathol Section Body Doc Link PMC3024921 Disease Relevance 1.41 Pain Relevance 0

General Comments

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