INT137449

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Context Info
Confidence 0.01
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.46
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (HEPN1)
HEPN1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Multiple sclerosis 1 95.94 Very High Very High Very High
fibrosis 1 78.40 Quite High
melanocortin 1 receptor 1 75.00 Quite High
Inflammation 4 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Neuritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Skin Cancer 2 100.00 Very High Very High Very High
Schizophrenia 1 100.00 Very High Very High Very High
Cold Sores 29 99.70 Very High Very High Very High
Cervical Cancer 2 99.18 Very High Very High Very High
Acquired Immune Deficiency Syndrome Or Hiv Infection 1 96.56 Very High Very High Very High
Demyelinating Disease 1 95.94 Very High Very High Very High
Reprotox - General 1 1 94.72 High High
Disease 58 92.00 High High
Spinocerebellar Ataxia Type 2 1 86.00 High High
Cystic Fibrosis 1 78.96 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This phenomenon appears to be universal, as vatches have been found in the XMRV virus, relating to human proteins involved in mitochondrial respiration and prostate cancer, in the Epstein-Barr virus, which matches multiple sclerosis autoantigens [27], in the AIDS virus which targets vatches in over 50 components of the human immune network, in the papillomavirus which targets cervical cancer oncogenes, and in the HSV-2 virus which targets schizophrenia susceptibility gene products (see http://www.polygenicpathways.co.uk/BLASTS.htm).
Positive_regulation (targets) of susceptibility gene associated with cervical cancer, multiple sclerosis, cold sores, acquired immune deficiency syndrome or hiv infection, schizophrenia and reprotox - general 1
1) Confidence 0.01 Published 2010 Journal International Journal of Alzheimer's Disease Section Body Doc Link PMC3018626 Disease Relevance 1.26 Pain Relevance 0.09
Exposure to UVR increases the synthesis of the photoprotective eumelanin on activation of MC1R, a melanoma susceptibility gene.
Positive_regulation (activation) of susceptibility gene associated with skin cancer
2) Confidence 0.00 Published 2006 Journal FASEB J. Section Abstract Doc Link 16877522 Disease Relevance 0.20 Pain Relevance 0.07

General Comments

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