INT137511

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Context Info
Confidence 0.61
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 5
Disease Relevance 1.90
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (OCA2) transport (OCA2) transmembrane transport (OCA2)
cytoplasm (OCA2)
Anatomy Link Frequency
eye 1
apoptotic cell 1
body 1
OCA2 (Homo sapiens)
Pain Link Frequency Relevance Heat
melanocortin 1 receptor 1 72.16 Quite High
Pain 1 67.80 Quite High
tolerance 6 5.00 Very Low Very Low Very Low
Central nervous system 3 5.00 Very Low Very Low Very Low
Parenteral administration 3 5.00 Very Low Very Low Very Low
headache 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 8 100.00 Very High Very High Very High
Death 2 100.00 Very High Very High Very High
Prostate Cancer 6 99.96 Very High Very High Very High
Sprains And Strains 2 96.28 Very High Very High Very High
Body Weight 24 89.60 High High
Immunotherapy Of Cancer 1 76.20 Quite High
Cancer 2 72.72 Quite High
Pain 1 67.80 Quite High
Skin Cancer 1 60.08 Quite High
Disorder Of Lipid Metabolism 6 28.16 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Similarly, we observed significantly increased levels of OCA2 mRNA in rs12913832-T (brown eye) homozygotes compared to rs12913832-C (blue eye) homozygous strains, which was not observed for MATP or NCKX5 gene transcripts.
Positive_regulation (increased) of OCA2 in eye associated with sprains and strains
1) Confidence 0.61 Published 2009 Journal J. Invest. Dermatol. Section Abstract Doc Link 18650849 Disease Relevance 0.19 Pain Relevance 0.07
The measures of muscular performance (1-RM and RTF total) increased in both the SOmaxP and CP cohorts, though by a higher percentage in the SOmaxP group.
Positive_regulation (increased) of SOmaxP
2) Confidence 0.41 Published 2010 Journal J Int Soc Sports Nutr Section Body Doc Link PMC3016253 Disease Relevance 0 Pain Relevance 0
The measures of muscular performance (1-RM and RTF total) increased in both the SOmaxP and CP cohorts, though by a higher percentage in the SOmaxP group.
Positive_regulation (percentage) of SOmaxP
3) Confidence 0.30 Published 2010 Journal J Int Soc Sports Nutr Section Body Doc Link PMC3016253 Disease Relevance 0 Pain Relevance 0
Lean body mass increased in the SOmaxP group from 62.7 kg to 64.2 kg (2.4% increase), while the CP cohort increased marginally from 62.6 kg to 62.8 kg (0.3% increase).
Positive_regulation (increased) of SOmaxP in body
4) Confidence 0.30 Published 2010 Journal J Int Soc Sports Nutr Section Body Doc Link PMC3016253 Disease Relevance 0.09 Pain Relevance 0
Here, we have shown that amygdalin induces apoptotic cell death in human DU145 and LNCaP prostate cancer cells by caspase-3 activation through down-regulation of Bcl-2 and up-regulation of Bax.
Positive_regulation (induces) of LNCaP in apoptotic cell associated with prostate cancer, apoptosis and death
5) Confidence 0.01 Published 2006 Journal Biol. Pharm. Bull. Section Abstract Doc Link 16880611 Disease Relevance 1.62 Pain Relevance 0.07

General Comments

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