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Context Info
Confidence 0.20
First Reported 1991
Last Reported 1991
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 1.32

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Oprd1, Ap2m1) lipid binding (Ap2m1) mitochondrion (Ap2m1)
vesicle-mediated transport (Ap2m1) cytoplasm (Oprd1) signal transducer activity (Oprd1)
Anatomy Link Frequency
tail 1
Oprd1 (Rattus norvegicus)
Ap2m1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
opioid receptor 2 100.00 Very High Very High Very High
Enkephalin 3 99.46 Very High Very High Very High
agonist 3 98.94 Very High Very High Very High
tail-flick 2 95.82 Very High Very High Very High
analgesia 7 95.46 Very High Very High Very High
Morphine 1 81.28 Quite High
Opioid 1 75.00 Quite High
Analgesic 1 52.88 Quite High


Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Since mu and delta opioid receptor subtypes have been implicated in supraspinal analgesia, the present study evaluated whether gender or adult gonadectomy altered (a) analgesia on the tail-flick and jump tests following central administration of the mu-selective agonist, [D-Ala2, Me-Phe4, Gly(ol)5] enkephalin (DAMGO) and the delta-selective agonist, [D-Ser2,Leu5] enkephalin-Thr6 (DSLET) and (b) mu1, mu2 and delta opioid receptor binding.
opioid receptor Binding (binding) of mu2 in tail associated with agonist, tail-flick, enkephalin, opioid receptor and analgesia
1) Confidence 0.20 Published 1991 Journal Pain Section Abstract Doc Link 1677751 Disease Relevance 0 Pain Relevance 1.32

General Comments

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