INT137563

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.59
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 3
Disease Relevance 0
Pain Relevance 0.87

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Ghrl, Npy) extracellular region (Ghrl, Npy) cytoplasm (Ghrl)
Anatomy Link Frequency
arcuate nucleus 2
Ghrl (Rattus norvegicus)
Npy (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Neuropeptide 6 100.00 Very High Very High Very High
Action potential 3 99.28 Very High Very High Very High
tetrodotoxin 3 98.80 Very High Very High Very High
sodium channel 3 97.96 Very High Very High Very High
Intracerebroventricular 3 88.16 High High
dexamethasone 3 84.20 Quite High

|}

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These data suggest that ghrelin stimulates NPY and AGRP gene expression independently of action potentials only in the presence of glucocorticoids.
ghrelin Positive_regulation (stimulates) of Gene_expression (expression) of NPY associated with action potential
1) Confidence 0.59 Published 2006 Journal Endocrinology Section Abstract Doc Link 16887908 Disease Relevance 0 Pain Relevance 0.28
Ghrelin also increased NPY heteronuclear (hn) RNA expression, the first transcript that has been used as an indicator for gene transcription.
Ghrelin Positive_regulation (increased) of Gene_expression (expression) of NPY
2) Confidence 0.40 Published 2006 Journal Endocrinology Section Abstract Doc Link 16887908 Disease Relevance 0 Pain Relevance 0.34
Ghrelin increases neuropeptide Y and agouti-related peptide gene expression in the arcuate nucleus in rat hypothalamic organotypic cultures.
Ghrelin Positive_regulation (increases) of Gene_expression (expression) of neuropeptide Y in arcuate nucleus associated with neuropeptide
3) Confidence 0.30 Published 2006 Journal Endocrinology Section Title Doc Link 16887908 Disease Relevance 0 Pain Relevance 0.25

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox