INT137619

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Context Info
Confidence 0.33
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

oxidoreductase activity (Cyp1a2) endoplasmic reticulum (Cyp1a2) enzyme binding (Cyp1a2)
response to stress (Cyp1a2)
Anatomy Link Frequency
Caco-2 1
Cyp1a2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
drug abuse 1 56.64 Quite High
Pain 1 55.68 Quite High
depression 1 55.20 Quite High
Disease Link Frequency Relevance Heat
Pain 1 5.00 Very Low Very Low Very Low
Depression 1 5.00 Very Low Very Low Very Low
Drug Dependence 1 5.00 Very Low Very Low Very Low
Psychosis 1 5.00 Very Low Very Low Very Low
Anxiety Disorder 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Selected compounds were screened for cytochrome P450 inhibition (CYP1A2, CYP2A6, CYP2B6, CYP2C8, CYP2C9, CYP2C19, CYP2D6, CYP2E1, CYP3A4), metabolic stability (rat and human liver microsomes), and cell-membrane permeability (Caco-2).
Protein_catabolism (stability) of CYP1A2 in Caco-2
1) Confidence 0.33 Published 2006 Journal ChemMedChem Section Abstract Doc Link 16892345 Disease Relevance 0 Pain Relevance 0.11

General Comments

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