INT137684

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Context Info
Confidence 0.02
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Cyp27b1, Prkca) cytoplasm (Cyp27b1, Prkca) aging (Cyp27b1)
endoplasmic reticulum (Prkca) enzyme binding (Prkca) protein complex (Prkca)
Anatomy Link Frequency
reticulum 1
Cyp27b1 (Mus musculus)
Prkca (Mus musculus)
Pain Link Frequency Relevance Heat
Kinase C 4 100.00 Very High Very High Very High
tricyclic antidepressant 1 74.72 Quite High
Pain 1 72.56 Quite High
Disease Link Frequency Relevance Heat
Pain 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In support of these results, COS cell transfection experiments show that phosphomimetic mutation Thr-35 --> Asp or induced cellular PKC caused increased CYP1A1 targeting to MT and correspondingly lower levels to the endoplasmic reticulum.
CYP1A1 Binding (targeting) of PKC in reticulum associated with kinase c
1) Confidence 0.02 Published 2006 Journal J. Biol. Chem. Section Abstract Doc Link 16899466 Disease Relevance 0 Pain Relevance 0.29

General Comments

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